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PE Anti-Ly6g 抗体 [RB6-8C5] (ab24884)

Submit a review Q&A (1)References (11)

Key features and details

  • PE Rat monoclonal [RB6-8C5] to Ly6g
  • Suitable for: Flow Cyt
  • Reacts with: Mouse
  • Conjugation: PE. Ex: 488nm, Em: 575nm
  • Isotype: IgG2b

Conjugates logo Related conjugates and formulations

APC Biotin FITC PE/Cy7® redFluor™ 710 Unconjugated violetFluor™ 450

製品の概要

  • 製品名

    PE Anti-Ly6g antibody [RB6-8C5]
    Ly6g 一次抗体 製品一覧

  • 製品の詳細

    PE Rat monoclonal [RB6-8C5] to Ly6g

  • 由来種

    Rat

  • 標識

    PE. Ex: 488nm, Em: 575nm

  • アプリケーション

    適用あり: Flow Cytmore details

  • 種交差性

    交差種: Mouse

  • 免疫原

    Tissue, cells or virus corresponding to Ly6g. Mouse granulocytes

  • 特記事項

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab24884の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
Flow Cyt
Use at an assay dependent concentration.
特記事項
Flow Cyt
Use at an assay dependent concentration.

ターゲット情報

  • 関連性

    Ly6G is a GPI-anchored protein, that is also known as the myeloid differentiation antigen Gr1. The antigen is transiently expressed on monocytes in the bone marrow. The level of antigen expression in the bone marrow directly correlates with granulocyte differentiation and maturation. Ly6G is expressed predominantly on neutrophils, also in a subset of eosinophils, differentiating pre-monocytes, and plasmacytoid dendritic cells.

  • 細胞内局在

    Attached to the membrane by a GPI-anchor.

  • 参照データベース

    • 別名

      • Gr-1 antibody
      • Gr1 antibody
      • Ly-6G.1 antibody
      • Ly6G antibody
      • Lymphocyte antigen 6 complex locus G antibody
      • Lymphocyte antigen 6G antibody
      see all

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (11)

    ab24884 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab24884 は 11 報の論文で使用されています。

    • Tumpey TM  et al. Neutrophil-mediated suppression of virus replication after herpes simplex virus type 1 infection of the murine cornea. J Virol 70:898-904 (1996). PubMed: 8551629
    • Lagasse E & Weissman IL Flow cytometric identification of murine neutrophils and monocytes. J Immunol Methods 197:139-50 (1996). PubMed: 8890901
    • Rakhmilevich AL Neutrophils are essential for resolution of primary and secondary infection with Listeria monocytogenes. J Leukoc Biol 57:827-31 (1995). PubMed: 7790763
    • Czuprynski CJ  et al. Administration of anti-granulocyte mAb RB6-8C5 impairs the resistance of mice to Listeria monocytogenes infection. J Immunol 152:1836-46 (1994). PubMed: 8120393
    • Conlan JW & North RJ Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody. J Exp Med 179:259-68 (1994). PubMed: 8270870
    View all Publications for this product

    レビューと Q&A

    Show All レビュー Q&A
    レビューを送る 質問を送る

    Question

    The question is where Ly6g existed, in the cell membrane, cytoplasm or nucleus? Thank you very much.

    Read More
    Answer



    This protein is a surface molecule and should be localized on the cell membrane, attached by a GPI-anchor.

    Read More

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