PE Anti-Interferon gamma 抗体 [CC302] (ab27866)
Key features and details
- PE Mouse monoclonal [CC302] to Interferon gamma
- Suitable for: Flow Cyt
- Reacts with: Sheep, Goat, Horse, Cow, Dog, Human, Pig, Ferret
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
製品の概要
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製品名
PE Anti-Interferon gamma antibody [CC302]
Interferon gamma 一次抗体 製品一覧 -
製品の詳細
PE Mouse monoclonal [CC302] to Interferon gamma -
由来種
Mouse -
標識
PE. Ex: 488nm, Em: 575nm -
特異性
This antibody recognises bovine interferon gamma -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Sheep, Goat, Horse, Cow, Dog, Human, Pig, Ferret -
免疫原
The details of the immunogen for this antibody are not available.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Do Not Freeze. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
CC302 -
ミエローマ
Sp2/0 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab27866の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt | (1) |
1/1 - 1/10.
ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. Neat - 1/10. Use 10µl of the suggested working dilution to label 106 cells in 100µl. Membrane permeabilisation is required for this application. |
特記事項 |
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Flow Cyt
1/1 - 1/10. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. Neat - 1/10. Use 10µl of the suggested working dilution to label 106 cells in 100µl. Membrane permeabilisation is required for this application. |
ターゲット情報
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機能
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. -
組織特異性
Released primarily from activated T lymphocytes. -
関連疾患
In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis. -
配列類似性
Belongs to the type II (or gamma) interferon family. -
翻訳後修飾
Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 281237 Cow
- Entrez Gene: 403801 Dog
- Entrez Gene: 100860815 Goat
- Entrez Gene: 100034181 Horse
- Entrez Gene: 3458 Human
- Entrez Gene: 396991 Pig
- Entrez Gene: 443396 Sheep
- Omim: 147570 Human
see all -
別名
- IF 1 antibody
- IFG antibody
- IFI antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (1)
ab27866 は 1 報の論文で使用されています。
- Mezhenskaya D et al. Universal Live-Attenuated Influenza Vaccine Candidates Expressing Multiple M2e Epitopes Protect Ferrets against a High-Dose Heterologous Virus Challenge. Viruses 13:N/A (2021). PubMed: 34209093