PE Anti-Hsp90 beta 抗体 (ab115641)
Key features and details
- PE Rabbit polyclonal to Hsp90 beta
- Suitable for: Flow Cyt (Intra)
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG
製品の概要
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製品名
PE Anti-Hsp90 beta antibody
Hsp90 beta 一次抗体 製品一覧 -
製品の詳細
PE Rabbit polyclonal to Hsp90 beta -
由来種
Rabbit -
標識
PE. Ex: 488nm, Em: 575nm -
アプリケーション
適用あり: Flow Cyt (Intra)more details -
種交差性
交差種: Human -
免疫原
Recombinant Human Hsp90 beta protein.
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ポジティブ･コントロール
- Jurkat cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
Preservative: 0.09% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab115641の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt (Intra) |
1/100.
|
| 特記事項 |
|---|
|
Flow Cyt (Intra)
1/100. |
ターゲット情報
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機能
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. -
配列類似性
Belongs to the heat shock protein 90 family. -
ドメイン
The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins. -
翻訳後修飾
Ubiquitinated in the presence of STUB1-UBE2D1 complex (in vitro).
ISGylated.
S-nitrosylated; negatively regulates the ATPase activity. -
細胞内局在
Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. - Information by UniProt
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参照データベース
- Entrez Gene: 3326 Human
- Omim: 140572 Human
- SwissProt: P08238 Human
- Unigene: 509736 Human
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別名
- 90 kda heat shock protein beta HSP90 beta antibody
- D6S182 antibody
- FLJ26984 antibody
see all
画像
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Flow Cytometry (Intracellular) - PE Anti-Hsp90 beta antibody (ab115641)ab115641 at 10µg/ml staining Hsp90 beta in 106 Jurkat cells by Flow cytometry (shown in red).
Grey: unstained;Yellow: isotype control.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab115641 は 3 報の論文で使用されています。
- Eng J et al. Cyclic Multiplexed-Immunofluorescence (cmIF), a Highly Multiplexed Method for Single-Cell Analysis. Methods Mol Biol 2055:521-562 (2020). PubMed: 31502168
- Gaglia G et al. HSF1 phase transition mediates stress adaptation and cell fate decisions. Nat Cell Biol 22:151-158 (2020). PubMed: 32015439
- Lin JR et al. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. Elife 7:N/A (2018). PubMed: 29993362