PE Anti-HLA G 抗体 [MEM-G/9] (ab24384)
Key features and details
- PE Mouse monoclonal [MEM-G/9] to HLA G
- Suitable for: Flow Cyt
- Reacts with: Recombinant fragment
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
PE Anti-HLA G antibody [MEM-G/9]
HLA G 一次抗体 製品一覧 -
製品の詳細
PE Mouse monoclonal [MEM-G/9] to HLA G -
由来種
Mouse -
標識
PE. Ex: 488nm, Em: 575nm -
特異性
The antibody reacts with native form of human HLA-G1 on the cell surface as well as with soluble HLA-G5 isoform in its beta2-microglobulin associated form. We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Recombinant fragment -
免疫原
Recombinant full length protein (Human) refolded with beta2-microglobulin and peptide.
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特記事項
The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: PBS, 0.2% BSA -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
MEM-G/9 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab24384の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use a concentration of 1 - 4 µg/ml.
Do not fix cells.ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
特記事項 |
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Flow Cyt
Use a concentration of 1 - 4 µg/ml. Do not fix cells.ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells. -
組織特異性
Expressed in trophoblasts. -
配列類似性
Belongs to the MHC class I family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain. -
細胞内局在
Membrane. - Information by UniProt
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別名
- B2 microglobulin antibody
- DADB-15K14.8 antibody
- HLA 6.0 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (12)
ab24384 は 12 報の論文で使用されています。
- Hamilton I et al. Utilizing primary HLA-G+ extravillous trophoblasts and HLA-G+ EVT-like cell lines to study maternal-fetal interactions. STAR Protoc 4:102276 (2023). PubMed: 37178111
- Eikmans M et al. Primary Trophoblast Cultures: Characterization of HLA Profiles and Immune Cell Interactions. Front Immunol 13:814019 (2022). PubMed: 35634345
- Nikoo S et al. Culture density of menstrual blood-derived stromal/stem cells determines the quality of T cell responses: An experimental study. Int J Reprod Biomed 19:75-86 (2021). PubMed: 33554005
- Carré T et al. Selection of tumor-resistant variants following sustained natural killer cell-mediated immune stress. Oncol Rep 45:582-594 (2021). PubMed: 33416152
- Sheridan MA et al. Establishment and differentiation of long-term trophoblast organoid cultures from the human placenta. Nat Protoc 15:3441-3463 (2020). PubMed: 32908314