PE Anti-HLA B7 抗体 [BB7.1] (ab33331)
Key features and details
- PE Mouse monoclonal [BB7.1] to HLA B7
- Suitable for: Flow Cyt
- Reacts with: Human, Monkey, Cynomolgus monkey
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
PE Anti-HLA B7 antibody [BB7.1]
HLA B7 一次抗体 製品一覧 -
製品の詳細
PE Mouse monoclonal [BB7.1] to HLA B7 -
由来種
Mouse -
標識
PE. Ex: 488nm, Em: 575nm -
特異性
This antibody binds to the HLA B7 antigen and does not cross react with HLA B27 or other related HLA antigens. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human, Monkey, Cynomolgus monkey -
免疫原
Full length protein corresponding to Human HLA B7. Papain solubilized HLA-B7 antigen.
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特記事項
This antibody can be used to distinguish true HLA B27 positives from false HLA B27 positives (i.e. HLA B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
This antibody was purified from tissue culture supernatant. -
一次抗体 備考
This antibody can be used to distinguish true HLA B27 positives from false HLA B27 positives (i.e. HLA B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis. -
ポリ/モノ
モノクローナル -
クローン名
BB7.1 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab33331の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
(or 100ul whole blood). ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. (or 100ul whole blood). ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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関連性
HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described. -
細胞内局在
Cell Membrane, single pass type I membrane protein. -
参照データベース
- Entrez Gene: 3106 Human
- Omim: 142830 Human
- SwissProt: P01889 Human
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別名
- Abacavir hypersensitivity, susceptibility to antibody
- Drug-induced liver injury due to flucloxacillin antibody
- HLA B antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab33331 は 1 報の論文で使用されています。
- Viborg N et al. T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients. Oncoimmunology 8:e1663107 (2019). PubMed: 31741759