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PE Anti-DR4 抗体 [DR-4-02] (ab65810)

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Flow Cytometry - PE Anti-DR4 antibody [DR-4-02] (ab65810)

    Key features and details

    • PE Mouse monoclonal [DR-4-02] to DR4
    • Suitable for: Flow Cyt
    • Reacts with: Human
    • Conjugation: PE. Ex: 488nm, Em: 575nm
    • Isotype: IgG1

    Conjugates logo Related conjugates and formulations

    Carrier Free

    製品の概要

    • 製品名

      PE Anti-DR4 antibody [DR-4-02]
      DR4 一次抗体 製品一覧

    • 製品の詳細

      PE Mouse monoclonal [DR-4-02] to DR4

    • 由来種

      Mouse

    • 標識

      PE. Ex: 488nm, Em: 575nm

    • アプリケーション

      適用あり: Flow Cytmore details

    • 種交差性

      交差種: Human

    • 免疫原

      Recombinant fragment corresponding to Human DR4 (extracellular).

    • 特記事項

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    製品の特性

    アプリケーション

    The Abpromise guarantee

    Abpromise保証は、 次のテスト済みアプリケーションにおけるab65810の使用に適用されます

    アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

    アプリケーション Abreviews 特記事項
    Flow Cyt
    Use a concentration of 2 - 5 µg/ml.
    特記事項
    Flow Cyt
    Use a concentration of 2 - 5 µg/ml.

    ターゲット情報

    • 機能

      Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.

    • 組織特異性

      Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K562 erythroleukemia cells, MCF7 breast carcinoma cells and activated T-cells.

    • 配列類似性

      Contains 1 death domain.
      Contains 3 TNFR-Cys repeats.

    • 細胞内局在

      Membrane.
    • Information by UniProt

    • 参照データベース

      • 別名

        • Apo2 antibody
        • CD261 antibody
        • Cytotoxic TRAIL receptor antibody
        • Death receptor 4 antibody
        • DR4 antibody
        • NF related apoptosis-inducing ligand receptor 1 antibody
        • TNF receptor superfamily member 10a antibody
        • TNF-related apoptosis-inducing ligand receptor 1 antibody
        • TNFRSF10A antibody
        • TR10A_HUMAN antibody
        • TRAIL receptor 1 antibody
        • TRAIL-R1 antibody
        • TRAILR 1 antibody
        • TRAILR1 antibody
        • Tumor necrosis factor receptor superfamily member 10A antibody
        • Tumor necrosis factor receptor superfamily member 10a variant 2 antibody
        • Tumor necrosis factor receptor superfamily, member 10a antibody
        see all

      画像

      • Flow Cytometry - PE Anti-DR4 antibody [DR-4-02] (ab65810)
        Flow Cytometry - PE Anti-DR4 antibody [DR-4-02] (ab65810)
        Flow Cytometry analysis of CD261-transfected HEK-293 cells labeling DR4 with Anti-DR4 antibody [DR-4-02] (Phycoerythrin) (ab65810).

      参考文献 (0)

      ab65810 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

      ab65810 は論文での使用が確認できていません。

      レビューと Q&A

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      レビューを送る 質問を送る

      There are currently no Customer reviews or Questions for ab65810.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com