AB95698

PE/Cy5® Anti-CD90 / Thy1 抗体 [5E10]

Name: PE/Cy5® Anti-CD90 / Thy1 抗体 [5E10] (ab95698) | Abcam
Brand: Abcam Limited
SKU: AB95698
Price: 38000 JPY
Availability: InStock

PE/Cy5® Anti-CD90 / Thy1 antibody [5E10]

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(9 Publications)

Anti-CD90 / Thy1 antibody [5E10] conjugated to PE/Cy5® - suitable for flow cytometry, and reacts with human samples. Clone [5E10] is a mouse monoclonal antibody and one of the most commonly used clones for flow cytometry.

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別名を表示する

CD90, Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, THY1

1 Images

Flow Cytometry - PE/Cy5® Anti-CD90 / Thy1 antibody [5E10] (AB95698)

Flow Cyt

Supplier Data

Flow Cytometry - PE/Cy5® Anti-CD90 / Thy1 antibody [5E10] (AB95698)

Flow cytometry analysis of HEL (human bone marrow erythroleukemia cell line) cells labelling CD90/Thy1 with Mouse IgG1 K Isotype Control PE-Cyanine5 (blue histogram) or ab35698 (purple histogram). Total viable cells were used for analysis.

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

5E10

アイソタイプ

IgG1

軽鎖のタイプ

kappa

標識

PE/Cy5®

励起波長/蛍光波長

Ex: 496nm, Em: 667nm

キャリアフリー

交差種

Human

アプリケーション

Flow Cyt

applications

免疫原

Cell preparation containing THY1 protein. The exact immunogen used to generate this antibody is proprietary information.

P04216

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>5 μL (0.25 μg)/test</p>" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein G

バッファー組成

pH: 7.2 Preservative: 0.09% Sodium azide Constituents: BSA, PBS

出荷温度

Blue Ice

短期保存温度

+4°C

長期保存温度

+4°C

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).

Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

See full target information THY1

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文献 (9)

Recent publications for all applications. Explore the full list and refine your search

Materials today. Bio 31:101500 PubMed39944530

2025

Cardioprotective effects of hUCMSCs-Exosi-EGR1 MN patch in MI/RI by modulating oxidative stress and mitophagy.

Applications

Unspecified application

Species

Unspecified reactive species

Chen Huang,Xun Zhang,Shi-Xiong Wu,Qing Chang,Zhi-Kun Zheng,Jing Xu

Cells, tissues, organs 211:565-576 PubMed34348283

2021

Evaluation of the Effects of Human Bone Marrow Mesenchymal Stem Cells Conditioned Medium on Growth and Maturation of Mouse Ovarian Follicle after Vitrification.

Applications

Unspecified application

Species

Unspecified reactive species

Shahriyar Tork,Zahra Nadia Sharifi,Shabnam Movassaghi,Negar Molaeeghaleh,Shabnam Abdi

Archives of oral biology 119:104896 PubMed32932148

2020

Investigation of the effect of a time delay on the characteristics and survival of dental pulp stem cells from extracted teeth.

Applications

Unspecified application

Species

Unspecified reactive species

Smriti Aryal Ac,Md Sofiqul Islam,A R Samsudin

Radiology and oncology 52:152-159 PubMed30018518

2018

Selection Approach to Develop DNA Aptamers for a Stem-like Cell Subpopulation of Non-small Lung Cancer Adenocarcinoma Cell Line A549.

Applications

Unspecified application

Species

Unspecified reactive species

Mateja Vidic,Tina Smuc,Nika Janez,Michael Blank,Tomaz Accetto,Jan Mavri,Isis C Nascimento,Arthur A Nery,Henning Ulrich,Tamara T Lah

Scientific reports 6:34373 PubMed27687492

2016

Single-cell analysis reveals IGF-1 potentiation of inhibition of the TGF-β/Smad pathway of fibrosis in human keratocytes in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Tomislav Sarenac,Martin Trapecar,Lidija Gradisnik,Marjan Slak Rupnik,Dusica Pahor

Cell biology international 39:519-30 PubMed25573851

2015

Ultrastructural maturation of human bone marrow mesenchymal stem cells-derived cardiomyocytes under alternative induction of 5-azacytidine.

Applications

Unspecified application

Species

Unspecified reactive species

Abbas Piryaei,Masoud Soleimani,Mohammad Hassan Heidari,Mona Saheli,Razieh Rohani,Mohammadali Almasieh

Journal of autoimmunity 25:181-92 PubMed16263243

2005

Immunopathogenic role of TH1 cells in autoimmune diabetes: evidence from a T1 and T2 doubly transgenic non-obese diabetic mouse model.

Applications

Unspecified application

Species

Unspecified reactive species

Jung-Tung Hung,Jen-Hsiang Liao,Yu-Chung Lin,Hsiu-Ying Chang,Shu-Fen Wu,Tsung-Hsien Chang,John T Kung,Shie-Liang Hsieh,Hugh McDevitt,Huey-Kang Sytwu

Blood 83:2410-7 PubMed7513197

1994

Thy-1 expression is linked to functional properties of primitive hematopoietic progenitor cells from human umbilical cord blood.

Applications

Unspecified application

Species

Unspecified reactive species

H Mayani,P M Lansdorp

The Journal of experimental medicine 177:1331-42 PubMed7683034

1993

Expression of Thy-1 on human hematopoietic progenitor cells.

Applications

Unspecified application

Species

Unspecified reactive species

W Craig,R Kay,R L Cutler,P M Lansdorp

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

PE/Cy5® Anti-CD90 / Thy1 抗体 [5E10]

PE/Cy5® Anti-CD90 / Thy1 antibody [5E10]

Flow Cytometry - PE/Cy5® Anti-CD90 / Thy1 antibody [5E10] (AB95698)

関連する標識済み抗体及び組成の異なる製品 (6)

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

軽鎖のタイプ

標識

励起波長/蛍光波長

キャリアフリー

交差種

アプリケーション

免疫原

代替製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

組合せ製品

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存温度

長期保存温度

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (9)

Abcam product promise