AB95700

PE Anti-CD90 / Thy1 抗体 [5E10]

Name: PE Anti-CD90 / Thy1 抗体 [5E10] (ab95700) | Abcam
Brand: Abcam Limited
SKU: AB95700
Price: 25000 JPY
Availability: InStock

PE Anti-CD90 / Thy1 antibody [5E10]

Be the first to review this product! Submit a review

(6 Publications)

Anti-CD90 / Thy1 antibody [5E10] conjugated to PE - suitable for flow cytometry, and reacts with human samples. Clone [5E10] is a mouse monoclonal antibody and one of the most commonly used clones for flow cytometry.

Design your panel with our interactive flow cytometry panel builder. Click here.

別名を表示する

CD90, Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, THY1

1 Images

Flow Cytometry - PE Anti-CD90 / Thy1 antibody [5E10] (AB95700)

Flow Cyt

Unknown

Flow Cytometry - PE Anti-CD90 / Thy1 antibody [5E10] (AB95700)

Flow cytometry staining of Human erythroleukemia (HEL) cells with Mouse IgG1 kappa Isotype Control PE (open histogram) or ab95700 (filled histogram). Total viable cells were used for analysis.

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

5E10

アイソタイプ

IgG1

軽鎖のタイプ

kappa

標識

励起波長/蛍光波長

Ex: 480;565nm, Em: 578nm

キャリアフリー

交差種

Human

アプリケーション

Flow Cyt

applications

免疫原

Cell preparation containing THY1 protein. The exact immunogen used to generate this antibody is proprietary information.

P04216

style

left-column

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "5 µL for 10^6 Cells", "FlowCyt-species-notes": "<p><a href='/products/primary-antibodies/pe-mouse-igg1-b11-6-isotype-control-ab91357'>ab91357</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

style

left-column

style

left-column

出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein G

バッファー組成

pH: 7.2 Preservative: 0.09% Sodium azide

出荷温度

Blue Ice

短期保存温度

+4°C

長期保存温度

+4°C

style

left-column

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).

Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.

style

left-column

style

left-column

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

ターゲットの情報

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

See full target information THY1

style

left-column

文献 (6)

Recent publications for all applications. Explore the full list and refine your search

Turkish journal of biology = Turk biyoloji dergisi 46:400-413 PubMed37529007

2022

The investigation of diverse physiological and therapeutic impact of cellular-based products derived from human cumulus cells.

Applications

Unspecified application

Species

Unspecified reactive species

Derya Burukçu,Sema Yilmaz,Oya Alagöz,Cumhur Kaan Yaltirik,Erkut Attar,Fikrettin Şahin,Esra Aydemir

Bioengineered 12:12891-12904 PubMed34784837

2021

MiR-455-5p upregulation in umbilical cord mesenchymal stem cells attenuates endometrial injury and promotes repair of damaged endometrium via Janus kinase/signal transducer and activator of transcription 3 signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Dongyan Sun,Zhihe Jiang,Yanling Chen,Di Shang,Pan Miao,Jian Gao

PloS one 15:e0242960 PubMed33270690

2020

Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension.

Applications

Unspecified application

Species

Unspecified reactive species

William Salibe-Filho,Thaís L S Araujo,Everton G Melo,Luiza B C T Coimbra,Monica S Lapa,Milena M P Acencio,Orival Freitas-Filho,Vera Luiza Capelozzi,Lisete Ribeiro Teixeira,Caio J C S Fernandes,Fabio Biscegli Jatene,Francisco R M Laurindo,Mario Terra-Filho

Cell transplantation 26:867-878 PubMed28105983

2017

Effect of Bone Marrow Aspirate Concentrate-Platelet-Rich Plasma on Tendon-Derived Stem Cells and Rotator Cuff Tendon Tear.

Applications

Unspecified application

Species

Unspecified reactive species

Sun Jeong Kim,Da Hyun Song,Jong Wook Park,Silvia Park,Sang Jun Kim

Blood 83:2410-7 PubMed7513197

1994

Thy-1 expression is linked to functional properties of primitive hematopoietic progenitor cells from human umbilical cord blood.

Applications

Unspecified application

Species

Unspecified reactive species

H Mayani,P M Lansdorp

The Journal of experimental medicine 177:1331-42 PubMed7683034

1993

Expression of Thy-1 on human hematopoietic progenitor cells.

Applications

Unspecified application

Species

Unspecified reactive species

W Craig,R Kay,R L Cutler,P M Lansdorp

View all publications

style

left-column

style

left-column

style

right-column

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

PE Anti-CD90 / Thy1 抗体 [5E10]

PE Anti-CD90 / Thy1 antibody [5E10]

Flow Cytometry - PE Anti-CD90 / Thy1 antibody [5E10] (AB95700)

関連する標識済み抗体及び組成の異なる製品 (6)

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

軽鎖のタイプ

標識

励起波長/蛍光波長

キャリアフリー

交差種

アプリケーション

免疫原

代替製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

組合せ製品

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存温度

長期保存温度

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (6)

Abcam product promise