PE Anti-CD80 抗体 [16-10A1] (ab93507)
![Flow Cytometry - PE Anti-CD80 antibody [16-10A1] (ab93507)](https://www.abcam.co.jp/ps/products/93/ab93507/Images/ab93507-276534-anti-cd80-antibody-16-10a1-phycoerythrin-flow-cytometry.jpg "Flow Cytometry - PE Anti-CD80 antibody [16-10A1] (ab93507)")
Key features and details
- PE Armenian hamster monoclonal [16-10A1] to CD80
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG
Related conjugates and formulations
製品の概要
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製品名
PE Anti-CD80 antibody [16-10A1]
CD80 一次抗体 製品一覧 -
製品の詳細
PE Armenian hamster monoclonal [16-10A1] to CD80 -
由来種
Armenian hamster -
標識
PE. Ex: 488nm, Em: 575nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse CD80. CHO cell line transfected with Mouse CD80
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ポジティブ･コントロール
- Activated Mouse splenocyte suspensions
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store undiluted. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, 0.14% Monobasic dihydrogen sodium phosphate, 0.1% Gelatin -
Concentration information loading... -
精製度
Affinity purified -
ポリ/モノ
モノクローナル -
クローン名
16-10A1 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab93507の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
ab101026 - Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. ab101026 - Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. -
組織特異性
Expressed on activated B-cells, macrophages and dendritic cells. -
配列類似性
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 12519 Mouse
- SwissProt: Q00609 Mouse
- Unigene: 89474 Mouse
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別名
- Activation B7-1 antigen antibody
- B lymphocyte activation antigen B7 antibody
- B7 antibody
see all
画像
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Flow Cytometry - PE Anti-CD80 antibody [16-10A1] (ab93507)
Flow Cytometry analysis of C57Bl/6 splenocytes unstimulated (left panel) or stimulated for 3 days with LPS (right panel) labeling CD80 with ab93507 at 0.125µg (solid line). Isotype control - Armenian Hamster IgG (Phycoerythrin) 0.125µg.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (7)
ab93507 は 7 報の論文で使用されています。
- Lei X et al. Mitochondrial Calcium Nanoregulators Reverse the Macrophage Proinflammatory Phenotype Through Restoring Mitochondrial Calcium Homeostasis for the Treatment of Osteoarthritis. Int J Nanomedicine 18:1469-1489 (2023). PubMed: 36998601
- Zhou X et al. In vivo self-assembled siRNA as a modality for combination therapy of ulcerative colitis. Nat Commun 13:5700 (2022). PubMed: 36171212
- Zhang L et al. Development of a Dendritic Cell/Tumor Cell Fusion Cell Membrane Nano-Vaccine for the Treatment of Ovarian Cancer. Front Immunol 13:828263 (2022). PubMed: 35251013
- Liu S et al. Structural characterization of a novel polysaccharide from Panax notoginseng residue and its immunomodulatory activity on bone marrow dendritic cells. Int J Biol Macromol 161:797-809 (2020). PubMed: 32553971
- Zhang B et al. NF-kappaB2 is required for the control of autoimmunity by regulating the development of medullary thymic epithelial cells. J Biol Chem 281:38617-24 (2006). PubMed: 17046818
- Odobasic D et al. Glomerular expression of CD80 and CD86 is required for leukocyte accumulation and injury in crescentic glomerulonephritis. J Am Soc Nephrol 16:2012-22 (2005). PubMed: 15944341
- Hancock WW et al. Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection. Proc Natl Acad Sci U S A 93:13967-72 (1996). PubMed: 8943044