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AB210350

PE Anti-CD4 抗体 [RM4-5]

PE Anti-CD4 antibody [RM4-5]

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(1 Publication)

Anti-CD4 antibody [RM4-5] conjugated to PE - suitable for flow cytometry, and reacts with mouse samples. Clone [RM4-5] is a rat monoclonal antibody and one of the most commonly used clones for flow cytometry.

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別名を表示する

CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

1 Images
Flow Cytometry - PE Anti-CD4 antibody [RM4-5] (AB210350)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE Anti-CD4 antibody [RM4-5] (AB210350)

Flow cytometric analysis of C57Bl/6 splenocytes labeling CD4 with 0.25 μg ab210350 (solid line), compared with 0.25 μg Phycoerythrin Rat IgG2a (dashed line).

関連する標識済み抗体及び組成の異なる製品 (6)

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    APC Anti-CD4 antibody [RM4-5]

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    APC/Cy7® Anti-CD4 antibody [RM4-5]

  • 519 FITC

    FITC Anti-CD4 antibody [RM4-5]

  • 778 PE/Cy7®

    PE/Cy7® Anti-CD4 antibody [RM4-5]

  • 704 redFluor™ 710

    redFluor™ 710 Anti-CD4 antibody [RM4-5]

  • 450 violetFluor™ 450

    violetFluor™ 450 Anti-CD4 antibody [RM4-5]

Key facts

宿主種

Rat

クローン性

Monoclonal

クローン番号

RM4-5

アイソタイプ

IgG2a

軽鎖のタイプ

kappa

標識

PE

励起波長/蛍光波長

Ex: 480;565nm, Em: 578nm

キャリアフリー

No

交差種

Mouse

アプリケーション

Flow Cyt

applications

特異性

The RM4-5 antibody is widely used as a phenotypic marker for CD4 expression.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use 0.25 μg per test</p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification
精製に関する特記事項
ab210350 was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
バッファー組成
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C
保管に関する情報
Store in the dark

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1) (PubMed : 12089508, PubMed : 16331979, PubMed : 2214026, PubMed : 9641677). Down-regulated by HIV-1 Vpu (PubMed : 17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed : 7909607).
See full target information CD4

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Nutrients 16: PubMed39683500

2024

Omega-3 Fatty Acids Weaken Lymphocyte Inflammatory Features and Improve Glycemic Control in Nonobese Diabetic Goto-Kakizaki Rats.

Applications

Unspecified application

Species

Unspecified reactive species

Tiago Bertola Lobato,Elvirah Samantha de Sousa Santos,Patrícia Nancy Iser-Bem,Henrique de Souza Falcão,Gabriela Mandú Gimenes,Janaina Ribeiro Barbosa Pauferro,Glayce Tavares Rodrigues,Ilana Souza Correa,Ana Carolina Gomes Pereira,Maria Elizabeth Pereira Passos,João Carlos de Oliveira Borges,Amara Cassandra Dos Anjos Alves,Camila Soares Dos Santos,Maria Janaina Leite de Araújo,Vinícius Leonardo Sousa Diniz,Adriana Cristina Levada-Pires,Tânia Cristina Pithon-Curi,Laureane Nunes Masi,Rui Curi,Sandro Massao Hirabara,Renata Gorjão
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