PE Anti-CD19 抗体 [CB19]
PE Anti-CD19 antibody [CB19]
- Lab Essentials
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(5 Publications)
Anti-CD19 antibody [CB19] conjugated to PE - suitable for flow cytometry, and reacts with human and Crab-Eating Macaque samples. Clone [CB19] is a mouse monoclonal antibody cited in 7 publications.
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別名を表示する
CD19, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12
- Flow Cyt
Supplier Data
Flow Cytometry - PE Anti-CD19 antibody [CB19] (AB1168)
Flow cytometry histogram showing 10µL of PE Anti-CD19 antibody [CB19] – (ab1168) used to stain 100µL of stabilized whole blood from healthy donor. A positive procedural control for T-lymphocyte, B-lymphocyte and NK cell enumeration (stabilized blood) was stained using mouse anti human CD19 RPE. Cells were gated on lymphocytes (using SSC/FSC dot plot). The first peak (near to the axis origin) shows negative cells (CD19-), the second peak shows the positive population, B cells according to the antibody specificity (CD19+).
Reactivity data
製品の詳細
PE Anti-CD19 antibody [CB19] (ab1168) is a mouse monoclonal antibody and is validated for use in Flow Cytometry (Flow Cyt) in Chimpanzee, Human, Macaque monkey, Rhesus monkey samples.
Related products
Antibody clone CB19 is also available pre-conjugated to a variety of labels for your convenience – Anti-CD19 PE [CB19] (ab1168).
Other related products
We have a range of other formats of antibody clone [CB19] also available for your convenience: ab254170, Carrier free - ab255925, Alexa Fluor® 647 - ab307266, FITC - ab1167, PE - ab1168
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出荷温度
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補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
CD19 acts as an essential player in B cell signaling. CD19 integrates signals from the BCR with other coreceptors acting as a signaling hub. It participates in forming a signaling complex that includes proteins like CD21 and CD81 which further amplifies BCR-mediated signaling. This complex plays a critical role in B cell activation differentiation and survival ensuring that immune responses are efficiently mounted against pathogens.
Pathways
The CD19 protein fits into key immune response pathways such as the BCR signaling pathway and the PI3K-Akt signaling pathway. CD19 collaborates with other proteins like CD21 CD81 and PI3K within these pathways. Its interaction in the PI3K-Akt pathway for instance supports critical processes including B cell activation and homeostasis contributing to the adaptive immune response.
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ターゲットの情報
文献 (5)
Recent publications for all applications. Explore the full list and refine your search
Scientific reports 15:5037 PubMed39934157
2025
Applications
Unspecified application
Species
Unspecified reactive species
Circulation 138:1144-1154 PubMed29593014
2018
Applications
Unspecified application
Species
Unspecified reactive species
Nature communications 8:14930 PubMed28374737
2017
Applications
Flow Cyt
Species
Unspecified reactive species
Journal of immunology (Baltimore, Md. : 1950) 149:2841-50 PubMed1383329
1992
Applications
Unspecified application
Species
Unspecified reactive species
Science (New York, N.Y.) 256:105-7 PubMed1373518
1992
Applications
Unspecified application
Species
Unspecified reactive species
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