Anti-PDE3B 抗体 (ab42091)
Key features and details
- Goat polyclonal to PDE3B
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG
製品の概要
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製品名
Anti-PDE3B antibody
PDE3B 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to PDE3B -
由来種
Goat -
特異性
Does not cross react with PDE4A variants nor with any other PDEs. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Recombinant fragment -
免疫原
Synthetic peptide within Human PDE3B aa 1050 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. Selective for only PDE3B variant.
Database link: Q13370 -
ポジティブ･コントロール
- WB: Human PDE3B protein
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C. -
バッファー
Antibody stabilization buffer, with preservatives, consisting of Hepes, NaCl, KCl, glycerol, BSA and chaotropic agents. -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab42091の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500. Detects a band of approximately 145 kDa (predicted molecular weight: 145 kDa).
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| 特記事項 |
|---|
|
WB
1/500. Detects a band of approximately 145 kDa (predicted molecular weight: 145 kDa). |
ターゲット情報
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機能
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. -
組織特異性
Abundant in adipose tissues. -
配列類似性
Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily. -
細胞内局在
Membrane. - Information by UniProt
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別名
- 5''-cyclic phosphodiesterase B antibody
- Adipocyte cAMP phosphodiesterase cGMP inhibited antibody
- AI847709 antibody
see all
画像
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Western blot - Anti-PDE3B antibody (ab42091)Anti-PDE3B antibody (ab42091) at 1/500 dilution + Human PDE3B protein
Predicted band size: 145 kDa
Observed band size: 145 kDa
データシートおよび資料
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Datasheet download
参考文献 (3)
ab42091 は 3 報の論文で使用されています。
- Guo CH et al. Combination of Fish Oil and Selenium Enhances Anticancer Efficacy and Targets Multiple Signaling Pathways in Anti-VEGF Agent Treated-TNBC Tumor-Bearing Mice. Mar Drugs 19:N/A (2021). PubMed: 33805447
- Yin C et al. PID1 alters the antilipolytic action of insulin and increases lipolysis via inhibition of AKT/PKA pathway activation. PLoS One 14:e0214606 (2019). PubMed: 30990811
- Guo CH et al. Effects of Chinese Medicinal Formula BNG-1 on Phosphodiesterase 3B Expression, Hepatic Steatosis, and Insulin Resistance in High Fat Diet-induced NAFLD Mice. Int J Med Sci 15:1194-1202 (2018). PubMed: 30123057
