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リコンビナントRabMAb

Anti-PCBP1 抗体 [EPR11049(B)] (ab168377)

Submit a review Submit a question References (4)
Western blot - Anti-PCBP1 antibody [EPR11049(B)] (ab168377)
  • Immunoprecipitation - Anti-PCBP1 antibody [EPR11049(B)] (ab168377)
  • Anti-PCBP1 antibody [EPR11049(B)] (ab168377)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR11049(B)] to PCBP1
  • Suitable for: WB, IP
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Carrier Free

製品の概要

  • 製品名

    Anti-PCBP1 antibody [EPR11049(B)]
    PCBP1 一次抗体 製品一覧

  • 製品の詳細

    Rabbit monoclonal [EPR11049(B)] to PCBP1

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: WB, IPmore details
    適用なし: Flow Cyt,ICC/IF or IHC-P

  • 種交差性

    交差種: Human
    交差が予測される動物種: Mouse, Rat

  • 免疫原

    Synthetic peptide corresponding to Human PCBP1.

  • ポジティブ･コントロール

    • HeLa, HepG2, K562 and 293T cell lysates.

  • 特記事項

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab168377の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
WB
1/1000 - 1/10000. Predicted molecular weight: 37 kDa.
IP
1/10 - 1/100.
特記事項
WB
1/1000 - 1/10000. Predicted molecular weight: 37 kDa.
IP
1/10 - 1/100.
追加情報
Is unsuitable for Flow Cyt,ICC/IF or IHC-P.

ターゲット情報

  • 機能

    Single-stranded nucleic acid binding protein that binds preferentially to oligo dC.

  • 組織特異性

    Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands.

  • 配列類似性

    Contains 3 KH domains.

  • 翻訳後修飾

    Phosphorylated; lowers poly(rC)-binding activity.

  • 細胞内局在

    Nucleus. Cytoplasm. Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.
  • Information by UniProt

  • 参照データベース

    • 別名

      • Alpha-CP1 antibody
      • Heterogeneous nuclear ribonucleoprotein E1 antibody
      • heterogenous nuclear ribonucleoprotein E1 antibody
      • heterogenous nuclear ribonucleoprotein X antibody
      • hnRNP E1 antibody
      • hnRNP-E1 antibody
      • hnRNP-X antibody
      • HNRPE1 antibody
      • HNRPX antibody
      • nucleic acid binding protein sub 2.3 antibody
      • Nucleic acid- binding protein SUB2.3 antibody
      • Nucleic acid-binding protein SUB2.3 antibody
      • PCBP1 antibody
      • PCBP1_HUMAN antibody
      • poly(rC) binding protein 1 antibody
      • Poly(rC)-binding protein 1 antibody
      • rCbinding protein 1 antibody
      see all

    画像

    • Western blot - Anti-PCBP1 antibody [EPR11049(B)] (ab168377)
      Western blot - Anti-PCBP1 antibody [EPR11049(B)] (ab168377)
      All lanes : Anti-PCBP1 antibody [EPR11049(B)] (ab168377) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HepG2 lysate
      Lane 3 : K562 cell lysate
      Lane 4 : 293T cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 37 kDa

    • Immunoprecipitation - Anti-PCBP1 antibody [EPR11049(B)] (ab168377)
      Immunoprecipitation - Anti-PCBP1 antibody [EPR11049(B)] (ab168377)
      Western blot analysis on HeLa cell lysate pellet immunoprecipitated using ab168377 at a 1/10 dilution, and an HRP-conjugated anti-rabbit IgG.
    • Anti-PCBP1 antibody [EPR11049(B)] (ab168377)
      Anti-PCBP1 antibody [EPR11049(B)] (ab168377)

    参考文献 (4)

    ab168377 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab168377 は 4 報の論文で使用されています。

    • Guo S  et al. TRIB2 modulates proteasome function to reduce ubiquitin stability and protect liver cancer cells against oxidative stress. Cell Death Dis 12:42 (2021). PubMed: 33414446
    • Yang J  et al. The Identification of Long Non-coding RNA H19 Target and Its Function in Chronic Myeloid Leukemia. Mol Ther Nucleic Acids 19:1368-1378 (2020). PubMed: 32160707
    • Lu Y  et al. SNHG1 Inhibits ox-LDL-Induced Inflammatory Response and Apoptosis of HUVECs via Up-Regulating GNAI2 and PCBP1. Front Pharmacol 11:703 (2020). PubMed: 32536864
    • Horiguchi H  et al. Extracellular vesicle miR-7977 is involved in hematopoietic dysfunction of mesenchymal stromal cells via poly(rC) binding protein 1 reduction in myeloid neoplasms. Haematologica 101:437-47 (2016). PubMed: 26802051

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