Anti-PARC 抗体 (ab115631)
Key features and details
- Rabbit polyclonal to PARC
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-PARC antibody -
製品の詳細
Rabbit polyclonal to PARC -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse
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免疫原
17 amino acid synthetic peptide, conjugated to KLH, from the C terminal region of Human PARC
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ポジティブ･コントロール
- Human testis tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab115631の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 特記事項 |
|---|
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IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Cytoplasmic anchor protein in p53-associated protein complex. Regulates the subcellular localization of p53 and subsequent function. Seems to be part of an atypical cullin-RING-based E3 ubiquitin-protein ligase complex. In vitro, complexes of CUL9/PARC with either CUL7 or TP53 contain E3 ubiquitin-protein ligase activity. -
組織特異性
Ubiquitously expressed in all tissues with highest expression in testis brain and kidney. -
配列類似性
Belongs to the cullin family.
Contains 1 DOC domain.
Contains 1 IBR-type zinc finger.
Contains 2 RING-type zinc fingers. -
ドメイン
The IBR domain is required for interaction with UBCH7 and UBCH8. -
翻訳後修飾
In vitro, self-ubiquitination in the presence of E1, E2 and ubiquitin.
Neddylated. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 23113 Human
- Entrez Gene: 78309 Mouse
- Omim: 607489 Human
- SwissProt: Q8IWT3 Human
- SwissProt: Q80TT8 Mouse
- Unigene: 485434 Human
- Unigene: 329076 Mouse
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別名
- CUL-9 antibody
- Cul9 antibody
- CUL9_HUMAN antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PARC antibody (ab115631)ab115631 at 5ug/ml staining PARC in Human testis tissue by immunohistochemistry (FFPE). Following primary incubation slides were incubated with biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab115631 は論文での使用が確認できていません。