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AB5787

Anti-PAR4 抗体

Anti-PAR4 antibody

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(7 Publications)

Rabbit Polyclonal PAR4 antibody. Suitable for WB and reacts with Rat samples. Cited in 7 publications. Immunogen corresponding to Synthetic Peptide within Human PAWR aa 300 to C-terminus.

別名を表示する

PAR4, PAWR, PRKC apoptosis WT1 regulator protein, Prostate apoptosis response 4 protein, Par-4

1 Images
Western blot - Anti-PAR4 antibody (AB5787)
  • WB

Supplier Data

Western blot - Anti-PAR4 antibody (AB5787)

All lanes:

Western blot - Anti-PAR4 antibody (ab5787)

All lanes:

Rat spleen extract

Predicted band size: 37 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Rat

アプリケーション

WB

applications

免疫原

Synthetic Peptide within Human PAWR aa 300 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q96IZ0

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "2 µg/mL", "WB-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
バッファー組成
Preservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Pro-apoptotic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Also seems to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.
See full target information PAWR
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文献 (7)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 26: PubMed40141421

2025

PAR Serves an Indispensable Role in Controlling PAR Oncogenicity: The β-Catenin-p53 Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Priyanga Appasamy,Jeetendra Kumar Nag,Hodaya Malka,Rachel Bar-Shavit

The American journal of pathology 192:361-378 PubMed35144762

2022

Vascular Endothelial Cells Produce Coagulation Factors That Control Their Growth via Joint Protease-Activated Receptor and C5a Receptor 1 (CD88) Signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Devin Cao,Michael G Strainic,Daniel Counihan,Shiva Sridar,Fengqi An,Wasim Hussain,Alvin H Schmaier,Marvin Nieman,M Edward Medof

Scientific reports 9:8755 PubMed31217499

2019

PAR-4 overcomes chemo-resistance in breast cancer cells by antagonizing cIAP1.

Applications

Unspecified application

Species

Unspecified reactive species

Haihong Guo,Fabian Treude,Oliver H Krämer,Bernhard Lüscher,Jörg Hartkamp

Human molecular genetics 20:1610-24 PubMed21282189

2011

A complex regulatory network of transcription factors critical for ocular development and disease.

Applications

IP

Species

Unspecified reactive species

Moulinath Acharya,Lijia Huang,Valerie C Fleisch,W Ted Allison,Michael A Walter

The Journal of biological chemistry 284:34829-38 PubMed19801652

2009

Human PRKC apoptosis WT1 regulator is a novel PITX2-interacting protein that regulates PITX2 transcriptional activity in ocular cells.

Applications

IHC-P, IHC-P, WB, WB

Species

Human, Mouse, Human, Mouse

Moulinath Acharya,David J Lingenfelter,Lijia Huang,Philip J Gage,Michael A Walter

Proceedings of the National Academy of Sciences of 106:12962-7 PubMed19470463

2009

Simultaneous inactivation of Par-4 and PTEN in vivo leads to synergistic NF-kappaB activation and invasive prostate carcinoma.

Applications

IHC-P

Species

Human

Pablo J Fernandez-Marcos,Shadi Abu-Baker,Jayashree Joshi,Anita Galvez,Elias A Castilla,Marta Cañamero,Manuel Collado,Carmen Saez,Gema Moreno-Bueno,Jose Palacios,Michael Leitges,Manuel Serrano,Jorge Moscat,Maria T Diaz-Meco

The Journal of endocrinology 194:77-85 PubMed17592023

2007

IGF-I inhibition of apoptosis is associated with decreased expression of prostate apoptosis response-4.

Applications

Unspecified application

Species

Unspecified reactive species

Hyunju Chung,Sanghee Seo,Minho Moon,Seungjoon Park
View all publications
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