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AB26816

Anti-Orthoreovirus fusion protein p10 抗体

Anti-Orthoreovirus fusion protein p10 antibody

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(1 Publication)

Rabbit Polyclonal Orthoreovirus fusion protein p10 antibody. Suitable for ELISA and reacts with Synthetic peptide - Avian orthoreovirus samples. Cited in 1 publication.

別名を表示する

Fusion protein p10

1 Images
ELISA - Anti-Orthoreovirus fusion protein p10 antibody (AB26816)
  • ELISA

Supplier Data

ELISA - Anti-Orthoreovirus fusion protein p10 antibody (AB26816)

ELISA using ab26816 at varying antibody concentrations and antigen concentration at 1000 ng/mL.

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Avian orthoreovirus

アプリケーション

ELISA

applications

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Avian orthoreovirus": { "ELISA-species-checked": "predicted", "ELISA-species-dilution-info": "", "ELISA-species-notes": "" }, "Synthetic peptide - Avian orthoreovirus": { "ELISA-species-checked": "testedAndGuaranteed", "ELISA-species-dilution-info": "1/40000", "ELISA-species-notes": "<p></p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The orthoreovirus fusion protein p10 also known as p10 protein plays an important role in cell membrane fusion contributing to viral entry into host cells. Its molecular mass is approximately 12 kDa. This protein is encoded by the orthoreovirus genome and is expressed in infected host cells during viral replication. p10 is important for the fusogenic activity that allows the virus to infect and spread between cells facilitating the viral life cycle.
Biological function summary

Orthoreovirus p10 fusion protein assists in mediating the formation of syncytia which are large multinucleated cells resulting from fusion. This function suggests that p10 is part of a larger fusogenic complex involving other viral proteins and host cell components. p10 curves the host cell membrane during the fusion process which further aids in the merging of viral and cellular membranes. This activity highlights its role in viral pathogenic mechanisms.

Pathways

Orthoreovirus p10 interacts with host cell signaling pathways involved in membrane rearrangement and immune responses. It interferes with normal metabolical functions to promote viral replication and spread. p10 protein's activity is associated with pathways related to membrane trafficking and reorganization working alongside proteins like orthoreovirus p14 and other viral fusogenic proteins. These interactions emphasize the protein's significance in viral infection pathways.

Orthoreovirus fusion protein p10 has links to viral-induced diseases including respiratory and gastrointestinal infections. The presence of p10 can aggravate inflammatory responses in these conditions. Connections to other viral proteins like p14 support the role of p10 in pathogenesis. These relationships are critical for understanding how orthoreovirus contributes to disease and provide insights for potential therapeutic targets.

製品プロトコール

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Plant methods 15:108 PubMed31548848

2019

Improving plant transient expression through the rational design of synthetic 5' and 3' untranslated regions.

Applications

Unspecified application

Species

Unspecified reactive species

Hadrien Peyret,James K M Brown,George P Lomonossoff
View all publications

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