Anti-Ornithine Carbamoyltransferase/OTC 抗体 [OTI8A1] (ab180401)
Key features and details
- Mouse monoclonal [OTI8A1] to Ornithine Carbamoyltransferase/OTC
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Ornithine Carbamoyltransferase/OTC antibody [OTI8A1]
Ornithine Carbamoyltransferase/OTC 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [OTI8A1] to Ornithine Carbamoyltransferase/OTC -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow -
免疫原
Recombinant full length protein corresponding to Human Ornithine Carbamoyltransferase/OTC aa 33-354. Mitochondrial Ornithine carbamoyltransferase (NP_000522)
Sequence:NKVQLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQKGEYLPLLQGKSL GMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGVNESLTDTARVLS SMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEH YSSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKL AEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAFQ GYQVTMKTAKVAASDWTFLHCLPRKPEEVDDEVFYSPRSLVFPEAENRKW TIMAVMVSLLTDYSPQLQKPKF
Database link: P00480 -
ポジティブ・コントロール
- Ornithine Carbamoyltransferase/OTC transfected HEK293T cell lysate.
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特記事項
The clone number has been updated from 8A1 to OTI8A1, both clone numbers name the same clone.
This product was changed from ascites to tissue culture supernatant on 29th May 2018. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 48% PBS, 50% Glycerol, 1% BSA -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
Purified from TCS -
ポリ/モノ
モノクローナル -
クローン名
OTI8A1 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab180401の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/2000. Predicted molecular weight: 39 kDa.
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特記事項 |
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WB
1/2000. Predicted molecular weight: 39 kDa. |
ターゲット情報
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組織特異性
Mainly expressed in liver and intestinal mucosa. -
パスウェイ
Nitrogen metabolism; urea cycle; L-citrulline from L-ornithine and carbamoyl phosphate: step 1/1. -
関連疾患
Ornithine carbamoyltransferase deficiency -
配列類似性
Belongs to the ATCase/OTCase family. -
翻訳後修飾
Acetylation at Lys-88 negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals. -
細胞内局在
Mitochondrion matrix. - Information by UniProt
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参照データベース
- Entrez Gene: 280887 Cow
- Entrez Gene: 5009 Human
- Entrez Gene: 18416 Mouse
- Entrez Gene: 25611 Rat
- Omim: 300461 Human
- SwissProt: Q9N1U7 Cow
- SwissProt: P00480 Human
- SwissProt: P11725 Mouse
see all -
別名
- EC 2.1.3.3 antibody
- MGC129967 antibody
- MGC129968 antibody
see all
画像
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All lanes : Anti-Ornithine Carbamoyltransferase/OTC antibody [OTI8A1] (ab180401) at 1/2000 dilution
Lane 1 : Non-transfected HEK293T cell lysate
Lane 2 : Lysate of HEK293T cells transfected with the pCMV6-ENTRY Ornithine Carbamoyltransferase / OTC cDNA.
Predicted band size: 39 kDa
HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC221568)
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab180401 は論文での使用が確認できていません。