Anti-OMD 抗体 (ab154249)
Key features and details
- Rabbit polyclonal to OMD
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-OMD antibody -
製品の詳細
Rabbit polyclonal to OMD -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Rat, Cow
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免疫原
Recombinant fragment, corresponding to a region within amino acids 174-402 of Human OMD.
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ポジティブ･コントロール
- A549 and MCF-7 whole cell lysates; Human colon cancer tissue; Mouse muscle tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab154249の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 49 kDa.
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| IHC-P |
1/100 - 1/1000.
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| 特記事項 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 49 kDa. |
|
IHC-P
1/100 - 1/1000. |
ターゲット情報
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機能
May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the alpha(V)beta(3)-integrin. -
組織特異性
Bone specific. -
配列類似性
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
Contains 11 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain. -
翻訳後修飾
Binds keratan sulfate chains. -
細胞内局在
Secreted, extracellular space, extracellular matrix. - Information by UniProt
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参照データベース
- Entrez Gene: 280885 Cow
- Entrez Gene: 4958 Human
- Entrez Gene: 27047 Mouse
- Entrez Gene: 83717 Rat
- SwissProt: O77742 Cow
- SwissProt: Q99983 Human
- SwissProt: O35103 Mouse
- SwissProt: Q9Z1S7 Rat
see all -
別名
- Keratan sulfate proteoglycan osteomodulin antibody
- KSPG osteomodulin antibody
- Omd antibody
see all
画像
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Western blot - Anti-OMD antibody (ab154249)All lanes : Anti-OMD antibody (ab154249) at 1/500 dilution
Lane 1 : A549 whole cell lysate
Lane 2 : MCF7 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 49 kDa
10% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OMD antibody (ab154249)Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue labeling OMD with ab154249 at 1/500 dilution. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OMD antibody (ab154249)Immunohistochemical analysis of paraffin-embedded mouse muscle tissue labeling OMD with ab154249 at 1/500 dilution.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab154249 は 1 報の論文で使用されています。
- Juchtmans N et al. Distinct dysregulation of the small leucine-rich repeat protein family in osteoarthritic acetabular labrum compared to articular cartilage. Arthritis Rheumatol 67:435-41 (2015). PubMed: 25371314