Anti-Olig2 抗体 (ab187740)
Key features and details
- Rabbit polyclonal to Olig2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Olig2 antibody
Olig2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Olig2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human Olig2 aa 100-200 (N terminal). The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using hetero bifunctional cross linker for Immunogen preparation.
Database link: Q13516 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.05% Sodium azide
stabilizing proteins (BSA), and glycerol. -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
ab187740 was purified on an immobilized antigen based affinity matrix. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab187740の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500. Detects a band of approximately 39 kDa (predicted molecular weight: 32 kDa).
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| 特記事項 |
|---|
|
WB
1/500. Detects a band of approximately 39 kDa (predicted molecular weight: 32 kDa). |
ターゲット情報
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機能
Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. -
組織特異性
Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. -
関連疾患
Note=A chromosomal aberration involving OLIG2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(14;21)(q11.2;q22) with TCRA. -
配列類似性
Contains 1 basic helix-loop-helix (bHLH) domain. -
ドメイン
The bHLH is essential for interaction with NKX2-2. -
細胞内局在
Nucleus. Cytoplasm. The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2. - Information by UniProt
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参照データベース
- Entrez Gene: 10215 Human
- Omim: 606386 Human
- SwissProt: Q13516 Human
- Unigene: 176977 Human
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別名
- Basic domain helix loop helix protein class B 1 antibody
- Basic helix loop helix protein class B 1 antibody
- BHLHB antibody
see all
画像
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Western blot - Anti-Olig2 antibody (ab187740)Anti-Olig2 antibody (ab187740) at 1/500 dilution + FOA 1 cell lysate
Predicted band size: 32 kDa
データシートおよび資料
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Datasheet download
参考文献 (0)
ab187740 は論文での使用が確認できていません。
