AB118565

Anti-OCIAD2 抗体

Name: Anti-OCIAD2 抗体 (ab118565) | Abcam
Brand: Abcam Limited
SKU: AB118565
Price: 81000 JPY
Availability: InStock

Anti-OCIAD2 antibody

Be the first to review this product! Submit a review

(3 Publications)

Rabbit Polyclonal OCIAD2 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human OCIAD2 conjugated to Keyhole Limpet Haemocyanin.

別名を表示する

OCIA domain-containing protein 2, Ovarian carcinoma immunoreactive antigen-like protein, OCIAD2

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OCIAD2 antibody (AB118565)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OCIAD2 antibody (AB118565)

ab118565, at 5 µg/ml, staining OCIAD2 in Formalin-fixed, Paraffin-embedded Human Kidney tissue by Immunohistochemistry.

Unknown

Western blot - Anti-OCIAD2 antibody (AB118565)

Lane 1:

Western blot - Anti-OCIAD2 antibody (ab118565) at 0.5 µg/mL

Lane 2:

Western blot - Anti-OCIAD2 antibody (ab118565) at 1 µg/mL

All lanes:

SK N SH cell lysate

Predicted band size: 17 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Human

アプリケーション

IHC-P, WB

applications

免疫原

Synthetic Peptide within Human OCIAD2 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q56VL3

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-1 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5 µg/mL", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

style

left-column

style

left-column

出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein A

バッファー組成

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

保管に関する情報

Avoid freeze / thaw cycle

style

left-column

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

OCIAD2 also known as ovarian cancer immunoreactive antigen domain containing 2 is a protein found in humans. It has a molecular mass of approximately 29 kDa. OCIAD2 is expressed in various tissues including the ovary breast and kidney. It localizes mainly in the cytoplasm and mitochondria suggesting a role in cellular processes related to these organelles.

Biological function summary

OCIAD2 impacts cellular processes through its involvement in cell differentiation and cellular stress responses. It may associate with multiprotein complexes that regulate these functions. Studies indicate OCIAD2 interacts with mitochondrial outer membrane components which hints it might play a role in mitochondrial dynamics. Through these interactions OCIAD2 contributes to maintaining cellular homeostasis during stress.

Pathways

OCIAD2 participates in pathways like oxidative phosphorylation and apoptosis. These pathways are important for cellular energy production and programmed cell death. OCIAD2 may interact with proteins such as cytochrome c and members of the Bcl-2 family in these processes. Through its involvement OCIAD2 helps regulate energy balance and cell survival influencing the fate of cells under various stimuli.

OCIAD2 has a connection to ovarian cancer and breast cancer. Abnormal expression of OCIAD2 associates with tumor progression and poor prognosis in ovarian cancer. In this context OCIAD2 might work with proteins like BRCA1 and HER2 which are critical in cancer biology. Understanding OCIAD2's role in these cancers could lead to potential therapeutic strategies or biomarkers for diagnosis.

style

left-column

style

left-column

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

ターゲットの情報

Has an essential role in the assembly of mitochondrial respiratory chain complex III (PubMed : 35080992). Is also required for STAT3 activation and plays a role in cell migration (PubMed : 29743632).

See full target information OCIAD2

style

left-column

文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Biomolecules & biomedicine 25:940-953 PubMed39466086

2024

Hsa_circ_0001492 regulates the hsa-miR-145-5p/ovarian carcinoma immunoreactive antigen domain 2 axis to promote the progression of lung adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yuanqiang He,Gang Li,Ran Fu,Yue Li,Ying Wang

Frontiers in pharmacology 13:777612 PubMed35295342

2022

The SKA3-DUSP2 Axis Promotes Gastric Cancer Tumorigenesis and Epithelial-Mesenchymal Transition by Activating the MAPK/ERK Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Chao Zhang,Shutao Zhao,Yuen Tan,Siwei Pan,Wen An,Qingchuan Chen,Xudong Wang,Huimian Xu

Annals of translational medicine 8:1670 PubMed33490182

2021

Proteomics and metabolomics of raw rhubarb and wine-processed rhubarb in the treatment of rats with intracerebral hemorrhage.

Applications

Unspecified application

Species

Unspecified reactive species

Kun Wang,Dongsheng Guan,Xu Zhao,Dongge Qiao,Yanhua Yang,Yinglin Cui

View all publications

style

left-column

style

left-column

style

right-column

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-OCIAD2 抗体

Anti-OCIAD2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OCIAD2 antibody (AB118565)

Western blot - Anti-OCIAD2 antibody (AB118565)

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

保管に関する情報

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (3)

組合せ製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Abcam product promise