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AB114096

Anti-NUP133 抗体

Anti-NUP133 antibody

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(1 Publication)

Rabbit Polyclonal NUP133 antibody. Suitable for IP and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human Nuclear pore complex protein Nup133 aa 650-700.

別名を表示する

Nuclear pore complex protein Nup133, 133 kDa nucleoporin, Nucleoporin Nup133, NUP133

1 Images
Immunoprecipitation - Anti-NUP133 antibody (AB114096)
  • IP

Unknown

Immunoprecipitation - Anti-NUP133 antibody (AB114096)

A rabbit anti-NUP133 antibody, at 1 µg/ml, staining NUP133 in HeLa whole cell lysate immunoprecipitated using ab114096 at 10 µg/mg lysate (1 mg for IP; 20% of IP loaded/lane). Detection : Chemiluminescence with an exposure time of 10 seconds.

All lanes:

Immunoprecipitation - Anti-NUP133 antibody (ab114096)

Predicted band size: 129 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

IP

applications

免疫原

Synthetic Peptide within Human Nuclear pore complex protein Nup133 aa 650-700. The exact immunogen used to generate this antibody is proprietary information.

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代替製品

Primary Antibodies

AB225215

Alexa Fluor® 647 Anti-NUP133 antibody [EPR10808(B)]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 647 Anti-NUP133 antibody [EPR10808(B)] (AB225215)

  • 5
  • 1
Primary Antibodies

AB181355

Anti-NUP133 antibody [EPR10809]

RabMAb|Recombinant

Western blot - Anti-NUP133 antibody [EPR10809] (AB181355)

  • 0
  • 0
Primary Antibodies

AB155990

Anti-NUP133 antibody [EPR10808(B)]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-NUP133 antibody [EPR10808(B)] (AB155990)

  • 5
  • 2
Primary Antibodies

AB236010

Anti-NUP133 antibody [EPR10808(B)] - BSA and Azide free

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-NUP133 antibody [EPR10808(B)] - BSA and Azide free (AB236010)

  • 0
  • 0

組合せ製品

Primary Antibodies

AB24700

Anti-Nup153 antibody [QE5]

Immunocytochemistry/ Immunofluorescence - Anti-Nup153 antibody [QE5] (AB24700)

  • 4
  • 5
Primary Antibodies

AB24609

Anti-Nuclear Pore Complex Proteins antibody [Mab414]

Immunocytochemistry/ Immunofluorescence - Anti-Nuclear Pore Complex Proteins antibody [Mab414] (AB24609)

  • 4
  • 12
Primary Antibodies

AB316336

Anti-RanBP2 antibody [RM2047]

BOND RX™ Validated|20ul selling size|Recombinant|RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RanBP2 antibody [RM2047] (AB316336)

  • 0
  • 0
Primary Antibodies

AB50610

Anti-NUP98 antibody [2H10] - Nuclear Pore Marker

Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-NUP98 antibody [2H10] - Nuclear Pore Marker (AB50610)

  • 4
  • 5
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "5-10 µg/mg of lysate", "IP-species-notes": "<p></p>" }, "Chimpanzee": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Gorilla": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Orangutan": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Rhesus monkey": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
精製に関する特記事項
ab114096 was affinity purified using an epitope specific to NUP133 immobilized on solid support.
バッファー組成
pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

NUP133 also known as nucleoporin 133 is a component of the nuclear pore complex. This protein weighs approximately 133 kDa. NUP133 localizes to the nuclear envelope and forms part of the structural scaffold of the nuclear pore. You will find expressions of this protein in a variety of cell types across different tissues. As an integral component of the nuclear pore complex NUP133 plays a role in transporting molecules between the nucleus and the cytoplasm.
Biological function summary

This protein is part of the Nup107-160 complex. This complex is essential for the assembly and maintenance of nuclear pores. NUP133 contributes to regulating the bidirectional transport of proteins and RNA across the nuclear envelope. It is involved in maintaining the structural integrity of the nuclear pore complex ensuring the selective exchange of substances between the nucleus and the cytoplasm. By doing so NUP133 influences various cellular processes like gene expression and DNA replication.

Pathways

The protein NUP133 engages primarily in the nucleocytoplasmic transport pathway. Within this framework it collaborates closely with other nucleoporins such as NUP107 and NUP160. The protein is also relevant in the regulation of the cell cycle as it ensures the proper formation and disassembly of nuclear pores during cell division. The interaction with other proteins within these pathways highlights the critical roles NUP133 fulfills in fundamental cellular activities.

Studies link NUP133 to certain cancer types including ovarian cancer and glioblastoma. Mutations or misregulation of NUP133 can lead to disturbances in nuclear transport and cellular proliferation contributing to tumorigenesis. The protein interacts with other members of the nuclear pore complex such as NUP85 underlining its potential impact in cancer progression. Understanding these associations may inform therapeutic strategies targeting nuclear transport pathways in related diseases.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Involved in poly(A)+ RNA transport. Involved in nephrogenesis (PubMed : 30179222).
See full target information Nuclear pore complex protein Nup133
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Cell discovery 8:130 PubMed36473865

2022

The chromatin remodeler CHD6 promotes colorectal cancer development by regulating TMEM65-mediated mitochondrial dynamics via EGF and Wnt signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Boyu Zhang,Qingxin Liu,Weijie Wen,Han Gao,Wenxia Wei,Aiwen Tang,Baifu Qin,Haiwen Lyu,Xiangqi Meng,Kai Li,Huilin Jin,Fenghai Yu,Qihao Pan,Junzhong Lin,Mong-Hong Lee
View all publications
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Abcam product promise

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