Anti-NKG2D 抗体 [1D11] (ab35033)
![Flow Cytometry - Anti-NKG2D antibody [1D11] (ab35033)](https://www.abcam.co.jp/ps/products/35/ab35033/Images/ab35033-48157-anti-nkg2d-antibody-1d11-flow-cytometry.gif "Flow Cytometry - Anti-NKG2D antibody [1D11] (ab35033)")
Key features and details
- Mouse monoclonal [1D11] to NKG2D
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
Anti-NKG2D antibody [1D11]
NKG2D 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [1D11] to NKG2D -
由来種
Mouse -
特異性
ab35033 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human NKG2D. NKL cells (Human)
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
1D11 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab35033の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
1/100.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
Flow Cyt
1/100. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. -
組織特異性
Natural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs). -
配列類似性
Contains 1 C-type lectin domain. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 100528032 Human
- Entrez Gene: 22914 Human
- Omim: 611817 Human
- SwissProt: P26718 Human
- Unigene: 387787 Human
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別名
- CD314 antibody
- CD314 antigen antibody
- D12S2489E antibody
see all
画像
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Flow Cytometry - Anti-NKG2D antibody [1D11] (ab35033)ab35033 staining NKG2D in human peripheral blood lymphocytes by Flow Cytometric analysis.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab35033 は 3 報の論文で使用されています。
- Fernández L et al. In vitro Natural Killer Cell Immunotherapy for Medulloblastoma. Front Oncol 3:94 (2013). Flow Cyt ; Human . PubMed: 23626949
- Abeyweera TP et al. Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells. J Cell Biol 192:675-90 (2011). Functional Studies ; Human . PubMed: 21339333
- Petukhova L et al. Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Nature 466:113-7 (2010). IHC-Fr ; Human . PubMed: 20596022