Anti-Nitrotyrosine 抗体 (ab42789)
Key features and details
- Rabbit polyclonal to Nitrotyrosine
- Suitable for: WB, ELISA, IHC-FoFr, IHC-P
- Isotype: IgG
製品の概要
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製品名
Anti-Nitrotyrosine antibody
Nitrotyrosine 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Nitrotyrosine -
由来種
Rabbit -
特異性
This antibody reacts with free and bound nitrotyrosine. There is no cross reaction with free or bound tyrosine -
アプリケーション
適用あり: WB, ELISA, IHC-FoFr, IHC-Pmore details -
種交差性
not applicable -
免疫原
Chemical/ Small Molecule corresponding to Nitrotyrosine conjugated to keyhole limpet haemocyanin.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Concentration information loading... -
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab42789の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (2) |
Use at an assay dependent concentration.
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| ELISA |
Use at an assay dependent concentration.
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| IHC-FoFr |
Use at an assay dependent concentration. PubMed: 22540017
|
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| IHC-P |
Use at an assay dependent concentration. PubMed: 24551153
|
| 特記事項 |
|---|
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WB
Use at an assay dependent concentration. |
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ELISA
Use at an assay dependent concentration. |
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IHC-FoFr
Use at an assay dependent concentration. PubMed: 22540017 |
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IHC-P
Use at an assay dependent concentration. PubMed: 24551153 |
ターゲット情報
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関連性
The cellular production of highly reactive nitrogen species derived from nitric oxide, such as peroxynitrite, nitrogen dioxide and nitryl chloride, leads to the nitration of tyrosine resides in tissue proteins. The extent of protein nitrotyrosine formation provides an index of the production of reactive nitrogen species and potential cell damage over a period of time. Nitrotyrosine can be measured by amino-acid analysis of protein hydrolysates and detected, estimated semi-quantitatively and located in cells and tissues by immunocytochemical techniques using antibodies directed against the nitrotyrosine hapten.
データシートおよび資料
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Datasheet download
参考文献 (23)
ab42789 は 23 報の論文で使用されています。
- Wang Y et al. Slow flow induces endothelial dysfunction by regulating thioredoxin-interacting protein-mediated oxidative metabolism and vascular inflammation. Front Cardiovasc Med 9:1064375 (2022). PubMed: 36465470
- Garcia-Irigoyen O et al. Enterocyte superoxide dismutase 2 deletion drives obesity. iScience 25:103707 (2022). PubMed: 35036884
- Đukić T et al. Proteomic Profiling of Major Peanut Allergens and Their Post-Translational Modifications Affected by Roasting. Foods 11:N/A (2022). PubMed: 36553735
- Patel B et al. Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain. Mol Metab 43:101123 (2021). PubMed: 33227495
- Török M et al. Network analysis of the left anterior descending coronary arteries in swim-trained rats by an in situ video microscopic technique. Biol Sex Differ 12:37 (2021). PubMed: 34039432
