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AB228587

Anti-NFkB Inducing Kinase NIK 抗体

Anti-NFkB Inducing Kinase NIK antibody

  • JP Hazardous:医薬用外毒物
  • JP Deleterious:医薬用外劇物

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(1 Publication)

Rabbit Polyclonal NFkB Inducing Kinase NIK antibody. Suitable for IHC-P, ICC/IF and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MAP3K14.

別名を表示する

NIK, MAP3K14, Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, Serine/threonine-protein kinase NIK, HsNIK

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-NFkB Inducing Kinase NIK antibody (AB228587)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-NFkB Inducing Kinase NIK antibody (AB228587)

K562 (human chronic myelogenous leukemia cell line from bone marrow ) cells stained for NFkB Inducing Kinase NIK (green) using ab228587 at 1/500 dilution in ICC/IF. Cells were fixed in ice-cold methanol for 5 minutes.

Blue : Hoechst 33342 staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NFkB Inducing Kinase NIK antibody (AB228587)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NFkB Inducing Kinase NIK antibody (AB228587)

Paraffin-embedded mouse prostate tissue stained for NFkB Inducing Kinase NIK with ab228587 at 1/500 dilution in immunohistochemical analysis.

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse, Human

アプリケーション

IHC-P, ICC/IF

applications

免疫原

Recombinant Fragment Protein within Human MAP3K14. The exact immunogen used to generate this antibody is proprietary information.

Q99558

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rhesus monkey": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
バッファー組成
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine)
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Phosphorylates CHUK/IKKA, thereby promoting proteolytic processing of NFKB2/P100, which leads to NF-kappa-B activation via the non-canonical pathway (PubMed : 25406581, PubMed : 29230214). Has an essential role in the non-canonical NF-kappa-B signaling that regulates genes encoding molecules involved in B-cell survival, lymphoid organogenesis, and immune response (PubMed : 25406581). Could act in a receptor-selective manner.
See full target information MAP3K14
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Oncogene 41:782-796 PubMed34853466

2021

GTF2E2 is a novel biomarker for recurrence after surgery and promotes progression of esophageal squamous cell carcinoma via miR-139-5p/GTF2E2/FUS axis.

Applications

Unspecified application

Species

Unspecified reactive species

Yujie Zhang,Yuxin Zhang,Bo Ai,Juejun Gong,Yichen Li,Shiying Yu,Xiuyu Cai,Li Zhang
View all publications
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代替製品

Primary Antibodies

AB203568

Anti-NFkB Inducing Kinase NIK antibody [3H31L48]

Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-NFkB Inducing Kinase NIK antibody [3H31L48] (AB203568)

  • 0
  • 0
Primary Antibodies

AB216409

Anti-NFkB Inducing Kinase NIK antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NFkB Inducing Kinase NIK antibody (AB216409)

  • 0
  • 0
Primary Antibodies

AB7204

Anti-NFkB Inducing Kinase NIK antibody

Immunocytochemistry/ Immunofluorescence - Anti-NFkB Inducing Kinase NIK antibody (AB7204)

  • 4
  • 2
Primary Antibodies

AB137671

Anti-NFkB Inducing Kinase NIK antibody - N-terminal

Western blot - Anti-NFkB Inducing Kinase NIK antibody - N-terminal (AB137671)

  • 0
  • 0

組合せ製品

Primary Antibodies

AB245752

Anti-MAP4K4/NIK antibody [SP177] - BSA and Azide free

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-MAP4K4/NIK antibody [SP177] - BSA and Azide free (AB245752)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB178872

Anti-IKK gamma/NEMO antibody [EPR16629]

RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IKK gamma/NEMO antibody [EPR16629] (AB178872)

  • 5
  • 1
Primary Antibodies

AB32041

Anti-IKK alpha antibody [Y463]

20ul selling size|RabMAb|Recombinant|KO Validated

Flow Cytometry (Intracellular) - Anti-IKK alpha antibody [Y463] (AB32041)

  • 4
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