AB216409

Anti-NFkB Inducing Kinase NIK 抗体

Name: Anti-NFkB Inducing Kinase NIK 抗体 (ab216409) | Abcam
Brand: Abcam Limited
SKU: AB216409
Price: 75000 JPY
Availability: InStock

Anti-NFkB Inducing Kinase NIK antibody

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(5 Publications)

Rabbit Polyclonal NFkB Inducing Kinase NIK antibody. Suitable for WB, IHC-P and reacts with Mouse, Rat samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human MAP3K14 aa 900 to C-terminus conjugated to Keyhole Limpet Haemocyanin.

別名を表示する

NIK, MAP3K14, Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, Serine/threonine-protein kinase NIK, HsNIK

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NFkB Inducing Kinase NIK antibody (AB216409)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NFkB Inducing Kinase NIK antibody (AB216409)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Rat brain tissue labeling NFkB Inducing Kinase NIK with ab216409 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

Supplier Data

Western blot - Anti-NFkB Inducing Kinase NIK antibody (AB216409)

10% gel

All lanes:

Western blot - Anti-NFkB Inducing Kinase NIK antibody (ab216409) at 1/200 dilution

Lane 1:

Mouse kidney lysate

Lane 2:

Mouse brain lysate

Secondary

All lanes:

Goat Anti-Rabbit IgG Antibody (H+L), HR at 1/3000 dilution

Predicted band size: 104 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Mouse, Rat

アプリケーション

IHC-P, WB

applications

免疫原

Synthetic Peptide within Human MAP3K14 aa 900 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q99558

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/100 - 1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p></p>" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein A

バッファー組成

pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Phosphorylates CHUK/IKKA, thereby promoting proteolytic processing of NFKB2/P100, which leads to NF-kappa-B activation via the non-canonical pathway (PubMed : 25406581, PubMed : 29230214). Has an essential role in the non-canonical NF-kappa-B signaling that regulates genes encoding molecules involved in B-cell survival, lymphoid organogenesis, and immune response (PubMed : 25406581). Could act in a receptor-selective manner.

See full target information MAP3K14

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文献 (5)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in oncology 13:1168772 PubMed37251946

2023

Identification of the hub genes associated with prostate cancer tumorigenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Honghui Zhu,Qi Lin,Xiaomin Gao,Xixi Huang

Evidence-based complementary and alternative medicine : eCAM 2022:4194827 PubMed35774743

2022

Network Pharmacology and In Vivo Analysis of Dahuang-Huangqi Decoction Effectiveness in Alleviating Renal Interstitial Fibrosis.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Luo,Chen Xuan,Junxiong Cheng,Yu Xiong,Wenfu Cao

Cell death & disease 13:58 PubMed35031599

2022

NEK2 enhances malignancies of glioblastoma via NIK/NF-κB pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jianyang Xiang,Wahafu Alafate,Wei Wu,Yichang Wang,Xiaodong Li,Wanfu Xie,Xiaobin Bai,Ruichun Li,Maode Wang,Jia Wang

Science advances 6: PubMed33208359

2020

Trappc9 deficiency in mice impairs learning and memory by causing imbalance of dopamine D1 and D2 neurons.

Applications

Unspecified application

Species

Unspecified reactive species

Yuting Ke,Meiqian Weng,Gaurav Chhetri,Muhammad Usman,Yan Li,Qing Yu,Yingzhuo Ding,Zejian Wang,Xiaolong Wang,Pinky Sultana,Marian DiFiglia,Xueyi Li

The American journal of pathology 190:252-269 PubMed31585070

2019

Host Lymphotoxin-β Receptor Signaling Is Crucial for Angiogenesis of Metanephric Tissue Transplanted into Lymphoid Sites.

Applications

Unspecified application

Species

Unspecified reactive species

Maria Giovanna Francipane,Bing Han,Eric Lagasse

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-NFkB Inducing Kinase NIK 抗体

Anti-NFkB Inducing Kinase NIK antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NFkB Inducing Kinase NIK antibody (AB216409)

Western blot - Anti-NFkB Inducing Kinase NIK antibody (AB216409)

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

代替製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

組合せ製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (5)

Abcam product promise