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AB203568

Anti-NFkB Inducing Kinase NIK 抗体 [3H31L48]

Anti-NFkB Inducing Kinase NIK antibody [3H31L48]

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(4 Publications)

Rabbit Recombinant Monoclonal NFkB Inducing Kinase NIK antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human MAP3K14 aa 700-900.

別名を表示する

NIK, MAP3K14, Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, Serine/threonine-protein kinase NIK, HsNIK

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-NFkB Inducing Kinase NIK antibody [3H31L48] (AB203568)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-NFkB Inducing Kinase NIK antibody [3H31L48] (AB203568)

Immunohistochemical analysis of non-transfected (left) and NIK transfected 293 cells (right) labeling NIK using ab203568 at 5 μg/mL. Alexa Fluor® 488 Goat anti-Rabbit at 1/1000 dilution was used as secondary antibody (green). Hoescht staining of nucleus (blue).

Western blot - Anti-NFkB Inducing Kinase NIK antibody [3H31L48] (AB203568)
  • WB

Supplier Data

Western blot - Anti-NFkB Inducing Kinase NIK antibody [3H31L48] (AB203568)

Lane 1:

anti FLAG tag antibody

Lane 2:

Western blot - Anti-NFkB Inducing Kinase NIK antibody [3H31L48] (ab203568) at 15 µg/mL

All lanes:

Flag tagged NIK transfected 293 cell lysate

Predicted band size: 104 kDa

false

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

3H31L48

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

WB, ICC/IF

applications

免疫原

Recombinant Fragment Protein within Human MAP3K14 aa 700-900. The exact immunogen used to generate this antibody is proprietary information.

Q99558

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "10-20 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "4-6 µg/mL", "ICCIF-species-notes": "<p></p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
Preservative: 0.09% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Phosphorylates CHUK/IKKA, thereby promoting proteolytic processing of NFKB2/P100, which leads to NF-kappa-B activation via the non-canonical pathway (PubMed : 25406581, PubMed : 29230214). Has an essential role in the non-canonical NF-kappa-B signaling that regulates genes encoding molecules involved in B-cell survival, lymphoid organogenesis, and immune response (PubMed : 25406581). Could act in a receptor-selective manner.
See full target information MAP3K14

文献 (4)

Recent publications for all applications. Explore the full list and refine your search

NPJ Regenerative medicine 8:6 PubMed36759627

2023

BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization.

Applications

Unspecified application

Species

Unspecified reactive species

Jiaqian Wang,Yuan Xue,Yi Wang,Chang Liu,Sihan Hu,Huan Zhao,Qiaoli Gu,Huilin Yang,Lixin Huang,Xichao Zhou,Qin Shi

PLoS pathogens 18:e1010110 PubMed35797416

2022

Recruitment of the CoREST transcription repressor complexes by Nerve Growth factor IB-like receptor (Nurr1/NR4A2) mediates silencing of HIV in microglial cells.

Applications

Unspecified application

Species

Unspecified reactive species

Fengchun Ye,David Alvarez-Carbonell,Kien Nguyen,Konstantin Leskov,Yoelvis Garcia-Mesa,Sheetal Sreeram,Saba Valadkhan,Jonathan Karn

BioMed research international 2020:1481572 PubMed32908868

2020

HuR Affects Proliferation and Apoptosis of Chronic Lymphocytic Leukemia Cells via NF-B Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Kai Xiao,Lin Yang,Xinfeng Gao,Ying An,Wei Xie,Guo Jingquan

International journal of molecular medicine 38:1661-1672 PubMed27840967

2016

Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-κB signaling pathways in osteoprotegerin knockout mice.

Applications

WB

Species

Mouse

Xue-Ju Li,Zhe Zhu,Si-Lin Han,Zi-Long Zhang
View all publications

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