Anti-Neurotensin Receptor 1/NTSR1 抗体 [B-N6] (ab27380)
Key features and details
- Mouse monoclonal [B-N6] to Neurotensin Receptor 1/NTSR1
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgM
製品の概要
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製品名
Anti-Neurotensin Receptor 1/NTSR1 antibody [B-N6]
Neurotensin Receptor 1/NTSR1 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [B-N6] to Neurotensin Receptor 1/NTSR1 -
由来種
Mouse -
特異性
Recognises the membrane protein.
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アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Neurotensin Receptor 1/NTSR1. NTR transfected CHO cell line
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.09% Sodium azide
Constituents: 98.91% PBS, 1% BSA -
Concentration information loading...
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特記事項(精製)
Gel filtration -
ポリ/モノ
モノクローナル -
クローン名
B-N6 -
ミエローマ
x63-Ag8.653 -
アイソタイプ
IgM -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab27380の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt |
Use 10µl for 106 cells.
ab91545 - Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody. |
特記事項 |
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Flow Cyt
Use 10µl for 106 cells. ab91545 - Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
G-protein coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:8381365, PubMed:21725197, PubMed:23140271). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis (PubMed:21725197). -
組織特異性
Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. Neurotensin receptor subfamily. NTSR1 sub-subfamily. -
ドメイン
The ligand binding pocket consists mainly of extracellular loops ECL2 and ECL3, as well as transmembrane regions TM6 and TM7. -
翻訳後修飾
N-gycosylated.
Palmitoylated; this is required for normal localization at membrane rafts and normal GNA11-mediated activation of down-stream signaling cascades. The palmitoylation level increases in response to neurotensin treatment. -
細胞内局在
Cell membrane. Membrane raft. Palmitoylation is required for localization at CAV1-enriched membrane rafts. - Information by UniProt
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参照データベース
- Entrez Gene: 4923 Human
- Omim: 162651 Human
- SwissProt: P30989 Human
- Unigene: 590869 Human
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別名
- High affinity levocabastine insensitive neurotensin receptor antibody
- High-affinity levocabastine-insensitive neurotensin receptor antibody
- Neurotensin receptor 1 (high affinity) antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab27380 は論文での使用が確認できていません。