Anti-Neuropeptide Y 抗体 [8] (ab112473)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neuropeptide Y antibody [8] (ab112473)](https://www.abcam.co.jp/ps/products/112/ab112473/Images/ab112473-125495-anti-neuropeptide-y-antibody-8-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neuropeptide Y antibody [8] (ab112473)")
Key features and details
- Mouse monoclonal [8] to Neuropeptide Y
- Suitable for: IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Neuropeptide Y antibody [8]
Neuropeptide Y 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [8] to Neuropeptide Y -
由来種
Mouse -
特異性
Cross-reactivity with Neuropeptide Y(1-24), Neuropeptide Y (18-36), Peptide YY or Pancreatic Polypeptide was <0.2%. -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Mouse, Human -
免疫原
Synthetic peptide corresponding to a region within Human/Rat Neuropeptide Y adsorbed onto aluminum hydroxide gel.
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エピトープ
The epitope of ab112473 is probably around the mid-molecular region of Neuropeptide Y. -
ポジティブ･コントロール
- Mouse brain tissue (fibres in the hilus of the hippocampus, following epiletic attack) Mouse brain tissue (interneurons in the cortex)
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.1% Sodium azide
Constituents: 2.9% Sodium chloride, 97% PBS -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
8 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab112473の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P | (1) |
1/1000.
|
| 特記事項 |
|---|
|
IHC-P
1/1000. |
ターゲット情報
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機能
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. -
組織特異性
One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. -
配列類似性
Belongs to the NPY family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 4852 Human
- Entrez Gene: 109648 Mouse
- Omim: 162640 Human
- SwissProt: P01303 Human
- SwissProt: P57774 Mouse
- Unigene: 1832 Human
- Unigene: 154796 Mouse
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別名
- C-flanking peptide of NPY antibody
- CPON antibody
- Neuropeptide tyrosine antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neuropeptide Y antibody [8] (ab112473)ab112473, at 1/1000, staining Neuropeptide Y in paraffin embedded Mouse brain tissue (fibres in the hilus of the hippocampus) from a mouse suffering an epiletic attack just before perfusion by Immunohistochemistry.
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neuropeptide Y antibody [8] (ab112473)](https://www.abcam.co.jp/ps/products/112/ab112473/Images/ab112473-125494-anti-neuropeptide-y-antibody-8-immunohistochemistry.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neuropeptide Y antibody [8] (ab112473)ab112473, at 1/1000, staining Neuropeptide Y in paraffin embedded Mouse brain tissue (fibres in the hilus of the hippocampus) from a mouse suffering an epiletic attack just before perfusion by Immunohistochemistry. -
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neuropeptide Y antibody [8] (ab112473)](https://www.abcam.co.jp/ps/products/112/ab112473/Images/ab112473-125493-anti-neuropeptide-y-antibody-8-immunohistochemistry.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neuropeptide Y antibody [8] (ab112473)ab112473, at 1/1000, staining Neuropeptide Y in paraffin embedded Mouse brain tissue (interneurons in the cortex) by Immunohistochemistry. -
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neuropeptide Y antibody [8] (ab112473)](https://www.abcam.co.jp/ps/products/112/ab112473/Images/ab112473-351540-anti-neuropeptide-y-antibody-8-immunohistochemistry-human-cerebral-cortex-2.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neuropeptide Y antibody [8] (ab112473)Immunofluorescence images of tissue from human cerebral cortex, applying ab112473 to ultra thin sections (antibody: green,
DAPI-stained nuclei: blue). The antibody labels NPY-positive processes in the neutrophil.
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neuropeptide Y antibody [8] (ab112473)](https://www.abcam.co.jp/ps/products/112/ab112473/Images/ab112473-241052-anti-neuropeptide-y-antibody-8-immunohistochemistry-human-cerebral-cortex.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neuropeptide Y antibody [8] (ab112473)Immunofluorescence images of tissue from human cerebral cortex, applying ab112473 to ultra thin sections (antibody: green,
DAPI-stained nuclei: blue). The antibody labels NPY-positive processes in the neutrophil.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (12)
ab112473 は 12 報の論文で使用されています。
- vonderEmbse AN et al. Developmental exposure to DDT or DDE alters sympathetic innervation of brown adipose in adult female mice. Environ Health 20:37 (2021). PubMed: 33794904
- Yuan S et al. Sympathetic activity is correlated with satellite cell aging and myogenesis via ß2-adrenoceptor. Stem Cell Res Ther 12:505 (2021). PubMed: 34530910
- Kluge N et al. Rapid measurement of cardiac neuropeptide dynamics by capacitive immunoprobe in the porcine heart. Am J Physiol Heart Circ Physiol 320:H66-H76 (2021). PubMed: 33095651
- Costantini I et al. Large-scale, cell-resolution volumetric mapping allows layer-specific investigation of human brain cytoarchitecture. Biomed Opt Express 12:3684-3699 (2021). PubMed: 34221688
- Hoang JD et al. Cardiac sympathetic activation circumvents high-dose beta blocker therapy in part through release of neuropeptide Y. JCI Insight 5:N/A (2020). PubMed: 32493842