Anti-Neuroligin 1 抗体 (ab153821)
Key features and details
- Rabbit polyclonal to Neuroligin 1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Neuroligin 1 antibody
Neuroligin 1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Neuroligin 1 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Cow
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免疫原
Recombinant fragment, corresponding to a region within amino acids 119-295 of Human Neuroligin 1.
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ポジティブ･コントロール
- U87-MG whole cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab153821の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 94 kDa.
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| 特記事項 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 94 kDa. |
ターゲット情報
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機能
Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. -
組織特異性
Expressed in the blood vessel walls (at protein level). -
配列類似性
Belongs to the type-B carboxylesterase/lipase family. -
細胞内局在
Cell membrane. Cell junction > synapse. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. - Information by UniProt
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参照データベース
- Entrez Gene: 22871 Human
- Entrez Gene: 192167 Mouse
- Omim: 600568 Human
- SwissProt: Q8N2Q7 Human
- SwissProt: Q99K10 Mouse
- Unigene: 478289 Human
- Unigene: 316080 Mouse
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別名
- NLG 1 antibody
- KIAA1070 antibody
- MGC45115 antibody
see all
画像
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Western blot - Anti-Neuroligin 1 antibody (ab153821)Anti-Neuroligin 1 antibody (ab153821) at 1/1000 dilution + U87-MG whole cell
lysate at 30 µg
Predicted band size: 94 kDa
7.5% SDS PAGE
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab153821 は 3 報の論文で使用されています。
- Xu J et al. Regulation of the Proliferation of Diabetic Vascular Endothelial Cells by Degrading Endothelial Cell Functional Genes with QKI-7. Contrast Media Mol Imaging 2022:6177809 (2022). PubMed: 35711530
- Xu K et al. CircGRIA1 shows an age-related increase in male macaque brain and regulates synaptic plasticity and synaptogenesis. Nat Commun 11:3594 (2020). PubMed: 32681011
- Yang C et al. Targeting QKI-7 in vivo restores endothelial cell function in diabetes. Nat Commun 11:3812 (2020). PubMed: 32732889