Anti-N Cadherin 抗体 (ab76057)
Key features and details
- Rabbit polyclonal to N Cadherin
- Suitable for: IP
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-N Cadherin antibody
N Cadherin 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to N Cadherin -
由来種
Rabbit -
特異性
ab76057 does not crossreact with E Cadherin. -
アプリケーション
適用あり: IPmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Rat, Chicken, Chimpanzee
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免疫原
Unphosphorylated synthetic peptide:
ERPIHAEPQYPVRS
, corresponding to amino acids 811-824 of Human N Cadherin (coupled to a carrier protein). This sequence is conserved in rat and mouse N cadherin, and has three amino acid differences from the conserved region in R Cadherin. -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 50% Glycerol, PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab76057の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IP |
1/100.
|
| 特記事項 |
|---|
|
IP
1/100. |
ターゲット情報
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機能
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. -
配列類似性
Contains 5 cadherin domains. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 414745 Chicken
- Entrez Gene: 12558 Mouse
- Entrez Gene: 83501 Rat
- SwissProt: P10288 Chicken
- SwissProt: P15116 Mouse
- SwissProt: Q9Z1Y3 Rat
- Unigene: 257437 Mouse
- Unigene: 23200 Rat
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別名
- CADH2_HUMAN antibody
- Cadherin 2 antibody
- Cadherin 2 N cadherin neuronal antibody
see all
画像
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Immunoprecipitation - Anti-N Cadherin antibody (ab76057)
Western blot image of mouse brain lysate immunoprecipitated with no antibody (lane 1), anti-N-Cadherin (CP1751) rabbit polyclonal antibody (lane 2), and whole mouse brain lysate (lane 3). The blot was probed with anti-N-cadherin (Cytoplasmic) mouse monoclonal antibody (lanes 1-3) and detected using anti-Mouse Ig Light Chain specific:HRP secondary antibody.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (217)
ab76057 は 217 報の論文で使用されています。
- Nakamura Y et al. A Complex of Type I Platelet-Activating Factor Acetylhydrolase (PAF-AH) Catalytic Subunits Switches from α1/α2 Heterodimer to α2/α2 Homodimer during Adipocyte Differentiation of 3T3-L1 Cells. Biol Pharm Bull 46:257-262 (2023). PubMed: 36724953
- Zhang B et al. MSX1 Regulates Goat Endometrial Function by Altering the Plasma Membrane Transformation of Endometrial Epithelium Cells during Early Pregnancy. Int J Mol Sci 24:N/A (2023). PubMed: 36835532
- Hayashi T et al. Effect of eribulin on epithelial-mesenchymal transition plasticity in metastatic breast cancer: An exploratory, prospective study. Genes Cells 28:364-373 (2023). PubMed: 36849792
- Schulz B et al. Analysis of connexin 43, connexin 45 and N-cadherin in the human sertoli cell line FS1 and the human seminoma-like cell line TCam-2 in comparison with human testicular biopsies. BMC Cancer 23:232 (2023). PubMed: 36899312
- Jiang C et al. BPTF in bone marrow provides a potential progression biomarker regulated by TFAP4 through the PI3K/AKT pathway in neuroblastoma. Biol Proced Online 25:11 (2023). PubMed: 37170211