Anti-Myosin 抗体 [MAC 147] (ab51098)
Key features and details
- Rat monoclonal [MAC 147] to Myosin
- Suitable for: Electron Microscopy, ICC/IF, WB
- Reacts with: Drosophila melanogaster, Waterbug
- Isotype: IgG1
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Myosin antibody [MAC 147]
Myosin 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [MAC 147] to Myosin -
由来種
Rat -
特異性
Reacts with subfagment 2 of Lethocerus and Drosophila myosin -
アプリケーション
適用あり: Electron Microscopy, ICC/IF, WBmore details -
種交差性
交差種: Drosophila melanogaster, Waterbug -
免疫原
Full length native protein (purified) corresponding to Waterbug Myosin.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
MAC 147 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab51098の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Electron Microscopy |
Use at an assay dependent concentration.
|
|
| ICC/IF | (2) |
Use at an assay dependent concentration.
|
| WB | (1) |
Use at an assay dependent concentration.
|
| 特記事項 |
|---|
|
Electron Microscopy
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. |
|
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Muscle contraction. -
配列類似性
Contains 1 IQ domain.
Contains 1 myosin head-like domain. -
ドメイン
The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.
Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). It can later be split further into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2). -
細胞内局在
Cytoplasm > myofibril. Thick filaments of the myofibrils. - Information by UniProt
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別名
- adult 1 antibody
- MYH1 antibody
- MYH1_HUMAN antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (10)
ab51098 は 10 報の論文で使用されています。
- Ribot C et al. Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy. PLoS Genet 18:e1010015 (2022). PubMed: 35025870
- Newton H et al. Systemic muscle wasting and coordinated tumour response drive tumourigenesis. Nat Commun 11:4653 (2020). PubMed: 32938923
- Di Cara F et al. Distinct Roles for Peroxisomal Targeting Signal Receptors Pex5 and Pex7 in Drosophila. Genetics 211:141-149 (2019). PubMed: 30389805
- Hessinger C et al. The Drosophila Hox gene Ultrabithorax acts in both muscles and motoneurons to orchestrate formation of specific neuromuscular connections. Development 144:139-150 (2017). PubMed: 27913640
- Molnár I et al. DAAM is required for thin filament formation and Sarcomerogenesis during muscle development in Drosophila. PLoS Genet 10:e1004166 (2014). ICC/IF ; Drosophila melanogaster . PubMed: 24586196
- Tarver MR et al. Myosin Gene Expression and Protein Abundance in Different Castes of the Formosan Subterranean Termite (Coptotermes formosanus). Insects 3:1190-9 (2012). PubMed: 26466734
- Hsu CY & Chan YP Identification and Localization of Proteins Associated with Biomineralization in the Iron Deposition Vesicles of Honeybees (Apis mellifera). PLoS One 6:e19088 (2011). WB ; Other species . PubMed: 21541330
- Deng H et al. Vestigial is required during late-stage muscle differentiation in Drosophila melanogaster embryos. Mol Biol Cell 21:3304-16 (2010). ICC/IF ; Drosophila melanogaster . PubMed: 20685961
- Qiu F et al. Myofilin, a protein in the thick filaments of insect muscle. J Cell Sci 118:1527-36 (2005). PubMed: 15769842
- Fyrberg E et al. Drosophila melanogaster troponin-T mutations engender three distinct syndromes of myofibrillar abnormalities. J Mol Biol 216:657-75 (1990). PubMed: 2124273