Anti-Myeloperoxidase 抗体 (ab9535)
Key features and details
- Rabbit polyclonal to Myeloperoxidase
- Suitable for: ICC, IHC-P
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Myeloperoxidase antibody
Myeloperoxidase 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Myeloperoxidase -
由来種
Rabbit -
アプリケーション
適用あり: ICC, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse
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免疫原
Full length native protein (purified) corresponding to Human Myeloperoxidase. Myeloperoxidase isolated from human granulocytes.
Database link: P05164 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.3
Preservative: 0.05% Sodium azide
Constituent: 1% BSA -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
ミエローマ
unknown -
アイソタイプ
IgG -
軽鎖の種類
unknown -
研究分野
関連製品
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Assay kits
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab9535の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC |
Use at an assay dependent concentration.
|
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| IHC-P | (28) |
1/25 - 1/50.
|
| 特記事項 |
|---|
|
ICC
Use at an assay dependent concentration. |
|
IHC-P
1/25 - 1/50. |
ターゲット情報
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機能
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. -
関連疾患
Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis. -
配列類似性
Belongs to the peroxidase family. XPO subfamily. -
細胞内局在
Lysosome. - Information by UniProt
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参照データベース
- Entrez Gene: 4353 Human
- Entrez Gene: 17523 Mouse
- Omim: 606989 Human
- SwissProt: P05164 Human
- SwissProt: P11247 Mouse
- Unigene: 458272 Human
- Unigene: 4668 Mouse
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別名
- 84 kDa myeloperoxidase antibody
- 89 kDa myeloperoxidase antibody
- EC 1.11.1.7 antibody
see all
画像
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Immunocytochemistry - Anti-Myeloperoxidase antibody (ab9535)Image courtesy of Carl Hobbs, Kings College London, U.K
Ab9535 staining of multinucleated cell (Blue) in human blood smear. Antibody was used at 1/200 for 1 hour at 21°C.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myeloperoxidase antibody (ab9535)Immunohistochemical analysis of formalin-fixed, paraffin-embedded human B cell lymphoma tissue, staining Myeloperoxidase with ab9535.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (320)
ab9535 は 320 報の論文で使用されています。
- Ogawa K et al. Association between tissue stress reaction and ACE2/TMPRSS2 expression in endometria of reproductive aged women before and during Covid-19 pandemic. BMC Womens Health 23:229 (2023). PubMed: 37142998
- Zhang Z et al. Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral Hemorrhage. Aging Dis 14:966-991 (2023). PubMed: 37191423
- Fleischman DA et al. Clinical and histopathological features of rostrolateral nasal alar arteriopathy of German shepherd dogs. Vet Dermatol 34:441-451 (2023). PubMed: 37221296
- Barreto-Arce LJ et al. Protection against brain injury after ischemic stroke by intravenous human amnion epithelial cells in combination with tissue plasminogen activator. Front Neurosci 17:1157236 (2023). PubMed: 37397458
- Lake BB et al. An atlas of healthy and injured cell states and niches in the human kidney. Nature 619:585-594 (2023). PubMed: 37468583