Anti-Myeloid Precursor Cells 抗体 [ER-MP58] (ab63860)
Key features and details
- Rat monoclonal [ER-MP58] to Myeloid Precursor Cells
- Suitable for: Flow Cyt, IHC-Fr, ICC/IF, IP
- Reacts with: Mouse
- Isotype: IgG2a
製品の概要
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製品名
Anti-Myeloid Precursor Cells antibody [ER-MP58] -
製品の詳細
Rat monoclonal [ER-MP58] to Myeloid Precursor Cells -
由来種
Rat -
アプリケーション
適用あり: Flow Cyt, IHC-Fr, ICC/IF, IPmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse Myeloid Precursor Cells. Balb/c macrophage precursor cell hybrids
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
ER-MP58 -
ミエローマ
Y3/Ag1.2.3 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab63860の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt | ||
| IHC-Fr | ||
| ICC/IF | ||
| IP |
| 特記事項 |
|---|
IHC-P: Use at an assay dependent dilution (PMID 19720836).
IHC-Fr: 1/25 - 1/100.
IP: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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関連性
ER-MP58 is expressed by all bone marrow derived M-CSF- and GM-CSF-responsive myeloid blood cell precursors. The expression of ER-MP58 remains at a high level throughout the precursor/monocyte stage and is down regulated upon maturation into mature macrophages. The ER-MP58 antigen is used to distinguish between early myeloid committed cells and other haematopoietic progenitors cells in the BM. -
細胞内局在
Cell Membrane
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab63860 は 2 報の論文で使用されています。
- Karpurapu M et al. Functional PU.1 in macrophages has a pivotal role in NF-?B activation and neutrophilic lung inflammation during endotoxemia. Blood 118:5255-66 (2011). Flow Cyt ; Mouse . PubMed: 21937699
- Lu X & Kang Y Chemokine (C-C motif) ligand 2 engages CCR2+ stromal cells of monocytic origin to promote breast cancer metastasis to lung and bone. J Biol Chem 284:29087-96 (2009). IHC-P ; Mouse . PubMed: 19720836