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AB20704

Anti-Mycoplasma pneumoniae 抗体

Anti-Mycoplasma pneumoniae antibody

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(1 Publication)

Rabbit Polyclonal Mycoplasma pneumoniae antibody. Suitable for IP, ICC/IF and reacts with Mycoplasma pneumoniae samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing Mycoplasma pneumoniae protein.

別名を表示する

M. pneumoniae, bacterial pneumonia

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Mycoplasma pneumoniae

アプリケーション

IP, ICC/IF

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

特異性

Recognises all Mycoplasma pneumoniae antigens. Has not been absorbed and so may react with related microorganisms. Not reactive with bovine or human sera.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mycoplasma pneumoniae": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
Preservative: 0.1% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Mycoplasma pneumoniae an atypical bacterium lacking a cell wall measures around 0.2 to 0.3 micrometers in size. It is commonly referred to as an "antibiotic-resistant pathogen." Mycoplasma pneumoniae localizes to the respiratory tract where it attaches to epithelial cells using specialized adhesion proteins. It interacts directly with the host cells impairing ciliary function and contributing to respiratory system inflammation. This bacterium has adapted to evade immune responses presenting challenges in treatment due to its resistance to cell wall-targeting antibiotics such as beta-lactams.
Biological function summary

Mycoplasma pneumoniae engages in several cellular processes that contribute to its pathogenesis. It does not appear to be part of a larger protein complex but utilizes a unique set of proteins for adherence and evasion of the immune response. This organism generates reactive oxygen species as byproducts which lead to tissue damage and dysfunction within host tissues. It has evolved mechanisms to modulate host immune reactions allowing it to persist and maintain infections over extended periods.

Pathways

Several associated with Mycoplasma pneumoniae are involved in immune modulation and inflammation. For instance it involves pathways related to cytokine production and epithelial cell signaling. These pathways interact with host proteins such as toll-like receptors augmenting the inflammatory response. Mycoplasma pneumoniae affects these signaling pathways influencing not only the localized respiratory tract environment but potentially broader systemic responses in the host.

Mycoplasma pneumoniae is notably associated with respiratory infections such as atypical pneumonia and it may contribute to the exacerbation of asthma symptoms. During infection it can interact with proteins like interleukin-6 in the inflammatory cascade potentially leading to heightened inflammatory responses. These interactions complicate underlying respiratory conditions making infections more severe and prolonged. Understanding these relationships highlights the need for developing specific anti-Mycoplasma pneumoniae antibodies and diagnostic tools to manage and treat infections effectively.

製品プロトコール

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Oncotarget 7:71817-71832 PubMed27708245

2016

Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE-/- Alzheimer's mouse model.

Applications

Unspecified application

Species

Unspecified reactive species

Stefan J Kempf,Dirk Janik,Zarko Barjaktarovic,Ignacia Braga-Tanaka,Satoshi Tanaka,Frauke Neff,Anna Saran,Martin R Larsen,Soile Tapio
View all publications

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