Anti-MX1 抗体 (ab95926)
Key features and details
- Rabbit polyclonal to MX1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-MX1 antibody
MX1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to MX1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Dog
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免疫原
Recombinant protein fragment corresponding to a region within amino acids 1 and 246 of Human MX1.
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ポジティブ･コントロール
- WB: H1299, HeLa, and Raji whole cell lysate; 293T, A431 and HepG2 whole cell lysate (ab7900) IHC-P: MDA-MB-468 xenograft
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
Purified by antigen affinity chromatography. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95926の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (2) |
1/500 - 1/3000. Predicted molecular weight: 76 kDa.
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| IHC-P | (6) |
1/100 - 1/500.
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| 特記事項 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 76 kDa. |
|
IHC-P
1/100 - 1/500. |
ターゲット情報
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機能
May regulate the calcium channel activity of TRPCs. Shows activity against influenza virus and VSV, a rhabdovirus. -
配列類似性
Belongs to the dynamin family.
Contains 1 GED domain. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 4599 Human
- Omim: 147150 Human
- SwissProt: P20591 Human
- Unigene: 517307 Human
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別名
- Human interferon regulated resistance GTP binding protein MXA antibody
- IFI 78 antibody
- IFI 78K antibody
see all
画像
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Western blot - Anti-MX1 antibody (ab95926)Lane 1 : Anti-MX1 antibody (ab95926) at 1/1000 dilution
Lane 2 : Anti-MX1 antibody (ab95926)
Lane 1 : 293T whole cell lysate/extract
Lane 2 : Human MX-1 transfected 293T cells
Lysates/proteins at 30 µg per lane.
Secondary
All lanes : HRP-conjugated anti-rabbit IgG antibody
Predicted band size: 76 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MX1 antibody (ab95926)Immunohistochemical analysis of paraffin embedded MDA-MB-468 xenograft, using ab95926 at a 1/500 dilution. -
Western blot - Anti-MX1 antibody (ab95926)All lanes : Anti-MX1 antibody (ab95926) at 1/5000 dilution
Lane 1 : H1299 cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : Raji cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 76 kDa
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (45)
ab95926 は 45 報の論文で使用されています。
- Zhu G et al. Type I Interferonopathy due to a Homozygous Loss-of-Inhibitory Function Mutation in STAT2. J Clin Immunol 43:808-818 (2023). PubMed: 36753016
- Brouiller F et al. Single-cell RNA-seq analysis reveals dual sensing of HIV-1 in blood Axl+ dendritic cells. iScience 26:106019 (2023). PubMed: 36866043
- Jurczyszak D et al. ISG15 deficiency restricts HIV-1 infection. PLoS Pathog 18:e1010405 (2022). PubMed: 35333911
- Filipe IC et al. Comparison of tissue tropism and host response to enteric and respiratory enteroviruses. PLoS Pathog 18:e1010632 (2022). PubMed: 35789345
- Zhou M et al. Activation of cGAS-STING pathway - A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy. J Clin Lab Anal 36:e24631 (2022). PubMed: 36030554