AB95926

Anti-MX1 抗体

Name: Anti-MX1 抗体 (ab95926) | Abcam
Brand: Abcam Limited
SKU: AB95926
Price: 88000 JPY
Availability: InStock
Rating: 5 (10 reviews)

Anti-MX1 antibody

(10 Reviews)

(55 Publications)

Anti-MX1 antibody (ab95926) is a rabbit polyclonal antibody detecting MX1 in Western Blot, IHC-P. Suitable for Human.

- Over 40 publications
- Trusted since 2010

別名を表示する

Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA, Myxoma resistance protein 1, Myxovirus resistance protein 1, IFI-78K, MX1

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Supplier Data

Western blot - Anti-MX1 antibody (AB95926)

Lane 1:

Western blot - Anti-MX1 antibody (ab95926) at 1/1000 dilution

Lane 2:

Western blot - Anti-MX1 antibody (ab95926)

Lane 1:

293T whole cell lysate/extract at 30 µg

Lane 2:

Human MX-1 transfected 293T cells at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 76 kDa

false

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MX1 antibody (AB95926)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MX1 antibody (AB95926)

Immunohistochemical analysis of paraffin embedded MDA-MB-468 xenograft, using ab95926 at a 1/500 dilution.

Supplier Data

Western blot - Anti-MX1 antibody (AB95926)

All lanes:

Western blot - Anti-MX1 antibody (ab95926) at 1/5000 dilution

Lane 1:

H1299 cell lysate at 30 µg

Lane 2:

HeLa cell lysate at 30 µg

Lane 3:

Raji cell lysate at 30 µg

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Human

アプリケーション

IHC-P, WB

applications

免疫原

Recombinant Fragment Protein within Human MX1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.

P20591

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }

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製品の詳細

What is this antibody validated in?
Anti-MX1 antibody (ab95926) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human samples.

What is the molecular weight of MX1?
Anti-MX1 (ab95926) specifically detects a band for MX1 (UniProt: P20591) at a molecular weight of 76kDa.

Trusted by the scientific community
Anti-MX1 (ab95926) was first used in a scientific publication in 2010 and has been cited over 40 times in peer-reviewed journals.

Reviewed by scientists
Anti-MX1 (ab95926) has over 10 independent reviews from customers.

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Immunogen

精製に関する特記事項

Purified by antigen affinity chromatography.

バッファー組成

pH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA

出荷温度

Blue Ice

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

See full target information MX1

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文献 (55)

Recent publications for all applications. Explore the full list and refine your search

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 133:e70034 PubMed40518873

2025

Immunohistochemical Profiling of Interferon-Stimulated Genes in Histopathological Specimens: A Potential Screening Approach for Viral Infections.

Applications

Unspecified application

Species

Unspecified reactive species

Christian Thomsen,Svend Birkelund,Rasmus Røge

Arthritis research & therapy 27:110 PubMed40389992

2025

Clinicopathological profile of eosinophilic fasciitis: a retrospective cohort study from a neuromuscular disorder center in China.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoyuan Wang,Lining Zhang,Ying Hou,Tingjun Dai,Xiaotian Ma,Kai Shao,Chuanzhu Yan,Bing Zhao

Arthritis research & therapy 26:215 PubMed39695751

2024

Development of differential diagnostic models for distinguishing between limb-girdle muscular dystrophy and idiopathic inflammatory myopathy.

Applications

Unspecified application

Species

Unspecified reactive species

Guangyu Wang,Lijun Fu,Lining Zhang,Kai Shao,Ying Hou,Tingjun Dai,Pengfei Lin,Chuanzhu Yan,Bing Zhao

Frontiers in immunology 15:1458967 PubMed39351233

2024

Varicella-zoster virus recapitulates its immune evasive behaviour in matured hiPSC-derived neurospheroids.

Applications

Unspecified application

Species

Unspecified reactive species

Jonas Govaerts,Elise Van Breedam,Sarah De Beuckeleer,Charlotte Goethals,Claudio Peter D'Incal,Julia Di Stefano,Siebe Van Calster,Tamariche Buyle-Huybrecht,Marlies Boeren,Hans De Reu,Søren R Paludan,Marc Thiry,Marielle Lebrun,Catherine Sadzot-Delvaux,Helena Motaln,Boris Rogelj,Johan Van Weyenbergh,Winnok H De Vos,Wim Vanden Berghe,Benson Ogunjimi,Peter Delputte,Peter Ponsaerts

iScience 27:110525 PubMed39156641

2024

Pandemic-associated pernio harbors footprints of an abortive SARS-CoV-2 infection.

Applications

Unspecified application

Species

Unspecified reactive species

Lisa M Arkin,Ana C Costa-da-Silva,Justin Frere,Ashley Ng,Rubina Sharma,John J Moon,Hailey E Bussan,Clara H Kim,Ayesha Javaid,Olivia R Steidl,Ahmad Yatim,Fanny Saidoune,Michel Gilliet,Joe T Nguyen,Aman Nihal,George Luong,Meaghan Kenfield,Lucia Carrau,Jennifer M Tran,Molly A Hinshaw,Erin G Brooks,Jose M Ayuso,David H O'Connor,Jean-Laurent Casanova,Edward W Cowen,Beth A Drolet,Anne Marie Singh,Benjamin tenOever,Jacqueline W Mays

CNS neuroscience & therapeutics 30:e14882 PubMed39097917

2024

Clinico-sero-pathological profiles and risk prediction model of idiopathic inflammatory myopathy (IIM) patients with different perifascicular changes.

Applications

Unspecified application

Species

Unspecified reactive species

Lining Zhang,Lijun Fu,Guoyong Zhang,Ying Hou,Xiaotian Ma,Dandan Zhao,Wei Li,Tingjun Dai,Qiang Shu,Chuanzhu Yan,Bing Zhao

Arthritis & rheumatology (Hoboken, N.J.) 76:78-91 PubMed37488975

2023

Endothelial Response to Type I Interferon Contributes to Vasculopathy and Fibrosis and Predicts Disease Progression of Systemic Sclerosis.

Applications

Unspecified application

Species

Unspecified reactive species

Hanlin Yin,Oliver Distler,Lichong Shen,Xiaojiang Xu,Ye Yuan,Rui Li,Bei Liu,Qianqian Li,Qianru Huang,Feng Xie,Zhiliang Zhang,Rui Liang,Xueyu Dai,Xiaoxiang Chen,Bin Li,Qingran Yan,Liangjing Lu

mBio 14:e0100723 PubMed37345956

2023

SARS-CoV-2 hijacks p38β/MAPK11 to promote virus replication.

Applications

Unspecified application

Species

Unspecified reactive species

Christina A Higgins,Benjamin E Nilsson-Payant,Boris Bonaventure,Andrew P Kurland,Chengjin Ye,Tomer M Yaron,Jared L Johnson,Prithy Adhikary,Ilona Golynker,Maryline Panis,Oded Danziger,Brad R Rosenberg,Lewis C Cantley,Luis Martínez-Sobrido,Benjamin tenOever,Jeffrey R Johnson

Journal of clinical immunology 43:808-818 PubMed36753016

2023

Type I Interferonopathy due to a Homozygous Loss-of-Inhibitory Function Mutation in STAT2.

Applications

Unspecified application

Species

Unspecified reactive species

Gaofeng Zhu,Mihaly Badonyi,Lina Franklin,Luis Seabra,Gillian I Rice, Anne-Boland-Auge,Jean-François Deleuze,Salima El-Chehadeh,Mathieu Anheim,Anne de Saint-Martin,Sandra Pellegrini,Joseph A Marsh,Yanick J Crow,Marie-Therese El-Daher

iScience 26:106019 PubMed36866043

2023

Single-cell RNA-seq analysis reveals dual sensing of HIV-1 in blood Axl dendritic cells.

Applications

Unspecified application

Species

Unspecified reactive species

Flavien Brouiller,Francesca Nadalin,Pierre-Emmanuel Bonté,Ouardia Ait-Mohamed,Constance Delaugerre,Jean-Daniel Lelièvre,Florent Ginhoux,Nicolas Ruffin,Philippe Benaroch

View all publications

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Abcam product promise

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