Anti-Muscarinic Acetylcholine Receptor M5/CHRM5 抗体 (ab150531)
Key features and details
- Rabbit polyclonal to Muscarinic Acetylcholine Receptor M5/CHRM5
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-Muscarinic Acetylcholine Receptor M5/CHRM5 antibody
Muscarinic Acetylcholine Receptor M5/CHRM5 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Muscarinic Acetylcholine Receptor M5/CHRM5 -
由来種
Rabbit -
特異性
BLAST analysis of the peptide immunogen showed no homology with other human proteins. -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Chimpanzee, Monkey, Gorilla, Common marmoset
-
免疫原
Synthetic peptide corresponding to Human Muscarinic Acetylcholine Receptor M5/CHRM5. Synthetic peptide corresponding to a 16 amino acid region within the 3rd cytoplasmic domain of Human Muscarinic Acetylcholine Receptor M5/CHRM5.
Database link: P08912 -
ポジティブ･コントロール
- Human brain tissue.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. -
バッファー
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab150531の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use a concentration of 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
| 特記事項 |
|---|
|
IHC-P
Use a concentration of 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
-
機能
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily. -
細胞内局在
Cell membrane. Cell junction, synapse, postsynaptic cell membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 503515 Chimpanzee
- Entrez Gene: 100404308 Common marmoset
- Entrez Gene: 1133 Human
- Entrez Gene: 101042089 Monkey
- Omim: 118496 Human
- SwissProt: Q5IS53 Chimpanzee
- SwissProt: P08912 Human
- SwissProt: Q5IS98 Monkey
see all -
別名
- Acetylcholine receptor muscarinic 5 antibody
- AChR antibody
- AChR M5 antibody
see all
画像
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Muscarinic Acetylcholine Receptor M5/CHRM5 antibody (ab150531)
Immunohistochemical analysis of formalin fixed, paraffin embedded Human brain tissue (vessel) labeling Muscarinic Acetylcholine Receptor M5/CHRM5 with ab150531 at 6 µg/ml.
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab150531 は 1 報の論文で使用されています。
- Wei W et al. Muscarinic cholinergic signaling and overactive bladder-like symptoms associated with invasive bladder cancer. Oncol Lett 16:775-784 (2018). PubMed: 29963145