Anti-Muscarinic Acetylcholine Receptor M3/CHRM3 抗体 (ab60981)
Key features and details
- Rabbit polyclonal to Muscarinic Acetylcholine Receptor M3/CHRM3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Muscarinic Acetylcholine Receptor M3/CHRM3 antibody
Muscarinic Acetylcholine Receptor M3/CHRM3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Muscarinic Acetylcholine Receptor M3/CHRM3 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Sheep, Horse, Hamster, Cow, Pig, Chimpanzee, Monkey, Gorilla, Common marmoset, Orangutan, Elephant -
免疫原
Synthetic peptide corresponding to Human Muscarinic Acetylcholine Receptor M3/CHRM3.
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ポジティブ・コントロール
- Heart tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.70
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab60981 was purified by peptide immunogen affinity column. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab60981の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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IHC-P
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM3 sub-subfamily. -
細胞内局在
Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Basolateral cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 469725 Chimpanzee
- Entrez Gene: 281685 Cow
- Entrez Gene: 101154508 Gorilla
- Entrez Gene: 1131 Human
- Entrez Gene: 100144478 Pig
- Omim: 118494 Human
- SwissProt: Q9N2A4 Chimpanzee
- SwissProt: P41984 Cow
see all -
別名
- AChR antibody
- ACM3_HUMAN antibody
- cholinergic receptor muscarinic 3 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Muscarinic Acetylcholine Receptor M3/CHRM3 antibody (ab60981)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue, staining Muscarinic Acetylcholine Receptor M3/CHRM3 with ab60981 at 10 µg/ml.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab60981 は 1 報の論文で使用されています。
- Müller JJ et al. Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation. J Vasc Res 54:259-271 (2017). PubMed: 28810262