Anti-MTTP/MTP 抗体 (ab75316)
Key features and details
- Rabbit polyclonal to MTTP/MTP
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-MTTP/MTP antibody
MTTP/MTP 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to MTTP/MTP -
由来種
Rabbit -
特異性
Reactivity with human samples appears to be lot-dependent. A user reported strong western blot reactivity with a mouse cell lysate but none with a human HepG2 lysate. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituent: Whole serum -
Concentration information loading... -
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab75316の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (1) |
1/200 - 1/2000. Detects a band of approximately 99 kDa (predicted molecular weight: 99 kDa).
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| 特記事項 |
|---|
|
WB
1/200 - 1/2000. Detects a band of approximately 99 kDa (predicted molecular weight: 99 kDa). |
ターゲット情報
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機能
Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B. -
組織特異性
Liver and small intestine. Also found in ovary, testis and kidney. -
関連疾患
Abetalipoproteinemia -
配列類似性
Contains 1 vitellogenin domain. -
細胞内局在
Endoplasmic reticulum. - Information by UniProt
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参照データベース
- Entrez Gene: 17777 Mouse
- SwissProt: O08601 Mouse
- Unigene: 2941 Mouse
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別名
- ABL antibody
- Microsomal triglyceride transfer protein (large polypeptide 88kDa) antibody
- Microsomal triglyceride transfer protein 88kD antibody
see all
画像
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Western blot - Anti-MTTP/MTP antibody (ab75316)Anti-MTTP/MTP antibody (ab75316) at 1/500 dilution + Liver (Mouse) Tissue Lysate at 10 µg
Secondary
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 99 kDa
Observed band size: 99 kDa
Additional bands at: 40 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 1 minute
データシートおよび資料
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Datasheet download
参考文献 (13)
ab75316 は 13 報の論文で使用されています。
- Yu K et al. In vivo functional characterization of EGFR variants identifies novel drivers of glioblastoma. Neuro Oncol 25:471-481 (2023). PubMed: 36044040
- Liu P et al. The DEAD-box helicase DDX3x ameliorates non-alcoholic fatty liver disease via mTORC1 signalling pathway. Liver Int 42:1793-1802 (2022). PubMed: 35460172
- Bhat N et al. Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice. J Clin Invest 132:N/A (2022). PubMed: 34855620
- Zhou C et al. Gadofullerene inhibits the degradation of apolipoprotein B100 and boosts triglyceride transport for reversing hepatic steatosis. Sci Adv 6:N/A (2020). PubMed: 32917715
- Gallego P et al. The Absence of NLRP3-inflammasome Modulates Hepatic Fibrosis Progression, Lipid Metabolism, and Inflammation in KO NLRP3 Mice during Aging. Cells 9:N/A (2020). PubMed: 32977490
