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AB182151

Anti-MS4A14 抗体 [EPR14020]

Anti-MS4A14 antibody [EPR14020]

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(2 Publications)

Rabbit Recombinant Monoclonal MS4A14 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications.

別名を表示する

MS4A13, MS4A16, MS4A14, Membrane-spanning 4-domains subfamily A member 14, Testis development protein NYD-SP21

2 Images
Western blot - Anti-MS4A14 antibody [EPR14020] (AB182151)
  • WB

Supplier Data

Western blot - Anti-MS4A14 antibody [EPR14020] (AB182151)

All lanes:

Western blot - Anti-MS4A14 antibody [EPR14020] (ab182151) at 1/20000 dilution

Lane 1:

THP1 cell lysate at 20 µg

Lane 2:

MCF7 cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 77 kDa

false

Western blot - Anti-MS4A14 antibody [EPR14020] (AB182151)
  • WB

Supplier Data

Western blot - Anti-MS4A14 antibody [EPR14020] (AB182151)

All lanes:

Western blot - Anti-MS4A14 antibody [EPR14020] (ab182151) at 1/20000 dilution

Lane 1:

Human thymus lysate at 10 µg

Lane 2:

Human testis lysate at 10 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab136636'>ab136636</a>) at 1/500 dilution

Predicted band size: 122 kDa,77 kDa

false

関連する標識済み抗体及び組成の異なる製品 (1)

  • Carrier free

    Anti-MS4A14 antibody [EPR14020] - BSA and Azide free

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR14020

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/10000 - 1/50000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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製品の詳細

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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出荷温度及び保存条件

製品の状態
Liquid
精製度
Tissue culture supernatant
バッファー組成
pH: 7.2 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

MS4A14 also known by its alternate names is part of the membrane-spanning 4-domains subfamily A. It has a molecular mass of approximately 54 kDa. This protein usually expresses in specific tissues such as the brain and testes. MS4A14 has a structure characterized by four transmembrane domains which indicates its role in cellular communication and membrane signaling processes.
Biological function summary

This protein participates in modulating signal transduction across the cellular membrane. MS4A14 associates with lipid rafts which facilitates its role in signaling events. It does not operate alone but as part of larger protein complexes interacting with other proteins to carry out its function. The precise complexes it forms are under continued research seeking to clarify its biological roles fully.

Pathways

This protein integrates within certain cellular signaling cascades. One important pathway it involves is the calcium-mediated signaling pathway. MS4A14 interacts with various proteins within this pathway such as calcium channels to help regulate ion flow across membranes. Another related pathway is immune response modulation though its exact partners in these cascades require further investigation to fully understand its integrative roles.

MS4A14 has links to Alzheimer's disease and certain forms of cancer. In Alzheimer's it interacts with proteins involved in amyloid-beta processing which plays an important role in disease progression. Its relation to cancer seems to connect to pathways influencing cell proliferation and apoptosis but the exact mechanisms and associated proteins are still subjects of active research. Understanding these connections could inform potential therapeutic targets.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

May be involved in signal transduction as a component of a multimeric receptor complex.
See full target information MS4A14
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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in immunology 13:853088 PubMed35651604

2022

Development of a Phagocytosis-Dependent Gene Signature to Predict Prognosis and Response to Checkpoint Inhibition in Clear-Cell Renal Cell Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Kunping Li,Yuqing Li,Yinfeng Lyu,Linyi Tan,Xinyi Zheng,Haowen Jiang,Hui Wen,Chenchen Feng

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 26:183-193 PubMed35477546

2022

Differentially expressed mRNAs and their upstream miR-491-5p in patients with coronary atherosclerosis as well as the function of miR-491-5p in vascular smooth muscle cells.

Applications

Unspecified application

Species

Unspecified reactive species

Hui Ding,Quanhua Pan,Long Qian,Chuanxian Hu
View all publications
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