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リコンビナントRabMAb

Anti-MRPS16 抗体 [EPR8835] (ab151693)

Submit a review Submit a question References (1)
Western blot - Anti-MRPS16 antibody [EPR8835] (ab151693)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS16 antibody [EPR8835] (ab151693)
  • Immunocytochemistry/ Immunofluorescence - Anti-MRPS16 antibody [EPR8835] (ab151693)
  • Anti-MRPS16 antibody [EPR8835] (ab151693)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR8835] to MRPS16
  • Suitable for: WB, IHC-P, ICC/IF
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Carrier Free

製品の概要

  • 製品名

    Anti-MRPS16 antibody [EPR8835]
    MRPS16 一次抗体 製品一覧

  • 製品の詳細

    Rabbit monoclonal [EPR8835] to MRPS16

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: WB, IHC-P, ICC/IFmore details
    適用なし: IP

  • 種交差性

    交差種: Human

  • 免疫原

    Synthetic peptide within Human MRPS16 aa 100-200 (C terminal). The exact sequence is proprietary.

  • ポジティブ･コントロール

    • HT1080, A673, HepG2 cell lysates; Human kidney tissue; HepG2 cells.

  • 特記事項

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab151693の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
WB
1/1000 - 1/10000. Predicted molecular weight: 15 kDa.
IHC-P
1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF
1/250 - 1/500.
特記事項
WB
1/1000 - 1/10000. Predicted molecular weight: 15 kDa.
IHC-P
1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF
1/250 - 1/500.
追加情報
Is unsuitable for IP.

ターゲット情報

  • 関連疾患

    Defects in MRPS16 are the cause of combined oxidative phosphorylation deficiency type 2 (COXPD2) [MIM:610498]. Defects in the mitochondrial oxidative phosphorylation system result in devastating, mainly multisystem, diseases. COXPD2 symptoms include fatal neonatal metabolic acidosis with agenesis of the corpus callosum.

  • 配列類似性

    Belongs to the ribosomal protein S16P family.

  • 細胞内局在

    Mitochondrion.
  • Information by UniProt

  • 参照データベース

    • 別名

      • 28S ribosomal protein S16 antibody
      • 28S ribosomal protein S16 mitochondrial antibody
      • CGI-132 antibody
      • COXPD2 antibody
      • mitochondrial antibody
      • Mitochondrial ribosomal protein S16 antibody
      • MRP-S16 antibody
      • mrps16 antibody
      • RPMS16 antibody
      • RT16_HUMAN antibody
      • S16mt antibody
      see all

    画像

    • Western blot - Anti-MRPS16 antibody [EPR8835] (ab151693)
      Western blot - Anti-MRPS16 antibody [EPR8835] (ab151693)
      All lanes : Anti-MRPS16 antibody [EPR8835] (ab151693) at 1/1000 dilution

      Lane 1 : HT1080 cell lysate
      Lane 2 : A673 cell lysate
      Lane 3 : HepG2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 15 kDa

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS16 antibody [EPR8835] (ab151693)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS16 antibody [EPR8835] (ab151693)

      Immunohistochemical analysis of paraffin-embedded Human kidney tissue labeling MRPS16 with ab151693 at 1/50 dilution.

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    • Immunocytochemistry/ Immunofluorescence - Anti-MRPS16 antibody [EPR8835] (ab151693)
      Immunocytochemistry/ Immunofluorescence - Anti-MRPS16 antibody [EPR8835] (ab151693)
      Immunofluorescent analysis of HepG2 cells labeling MRPS16 with ab151693 at 1/250 dilution.
    • Anti-MRPS16 antibody [EPR8835] (ab151693)
      Anti-MRPS16 antibody [EPR8835] (ab151693)

    参考文献 (1)

    ab151693 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab151693 は 1 報の論文で使用されています。

    • Wang Z  et al. MRPS16 facilitates tumor progression via the PI3K/AKT/Snail signaling axis. J Cancer 11:2032-2043 (2020). PubMed: 32127931

    レビューと Q&A

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