Anti-MRP5 抗体 (ab180724)
Key features and details
- Rabbit polyclonal to MRP5
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-MRP5 antibody
MRP5 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to MRP5 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Mouse, Human -
免疫原
Synthetic peptide corresponding to Human MRP5.
Database link: O15440 -
ポジティブ･コントロール
- Mouse heart lysate, Human lung cancer tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab180724の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
1/50 - 1/200.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
|
| WB |
1/1000 - 1/2000. Predicted molecular weight: 161 kDa.
|
| 特記事項 |
|---|
|
IHC-P
1/50 - 1/200. ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
|
WB
1/1000 - 1/2000. Predicted molecular weight: 161 kDa. |
ターゲット情報
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機能
Acts as a multispecific organic anion pump which can transport nucleotide analogs. -
配列類似性
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 10057 Human
- Entrez Gene: 27416 Mouse
- Omim: 605251 Human
- SwissProt: O15440 Human
- SwissProt: Q9R1X5 Mouse
- Unigene: 368563 Human
- Unigene: 728765 Human
- Unigene: 20845 Mouse
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別名
- ABC 33 antibody
- ABC33 antibody
- ABCC 5 antibody
see all
画像
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Western blot - Anti-MRP5 antibody (ab180724)Anti-MRP5 antibody (ab180724) at 1/1000 dilution + Jurkat cell lysate
Predicted band size: 161 kDa -
Western blot - Anti-MRP5 antibody (ab180724)Anti-MRP5 antibody (ab180724) at 1/1000 dilution + Mouse heart lysate
Predicted band size: 161 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRP5 antibody (ab180724)Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue labeling MRP5 with ab180724 at 1/50, right panel shows negative control.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab180724 は 3 報の論文で使用されています。
- Kurosawa T et al. Transport Characteristics of 6-Mercaptopurine in Brain Microvascular Endothelial Cells Derived From Human Induced Pluripotent Stem Cells. J Pharm Sci 110:3484-3490 (2021). PubMed: 34102205
- Koehn LM et al. Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfide. Sci Rep 9:5998 (2019). PubMed: 30979952
- Zhang L et al. miR-361 enhances sensitivity to 5-fluorouracil by targeting the FOXM1-ABCC5/10 signaling pathway in colorectal cancer. Oncol Lett 18:4064-4073 (2019). PubMed: 31579069