Anti-MRG15 抗体 (ab106818)
Key features and details
- Goat polyclonal to MRG15
- Suitable for: WB
- Reacts with: Mouse, Rat, Human, Pig
- Isotype: IgG
製品の概要
-
製品名
Anti-MRG15 antibody
MRG15 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to MRG15 -
由来種
Goat -
特異性
This antibody is expected to recognise both reported isoforms. -
アプリケーション
適用あり: WBmore details
適用なし: IHC-P -
種交差性
交差種: Mouse, Rat, Human, Pig
交差が予測される動物種: Cow -
免疫原
Synthetic peptide:
APKQDPKPKFQEG-C
, corresponding to N terminal amino acids 2-14 of Human MRG15 (NP_006782.1; NP_996670.1.) -
特記事項
This product will identify isoform 1 and isoform 2.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
-
精製度
Immunogen affinity purified -
特記事項(精製)
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106818の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 41 kDa.
1 hour primary incubation is recommended for this product. |
特記事項 |
---|
WB
Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 41 kDa. 1 hour primary incubation is recommended for this product. |
ターゲット情報
-
機能
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci. -
配列類似性
Belongs to the MRG family. -
細胞内局在
Nucleus. - Information by UniProt
-
参照データベース
- Entrez Gene: 614390 Cow
- Entrez Gene: 10933 Human
- Entrez Gene: 21761 Mouse
- Entrez Gene: 627352 Mouse
- Entrez Gene: 100154823 Pig
- Entrez Gene: 300891 Rat
- Omim: 607303 Human
- SwissProt: Q9UBU8 Human
see all -
別名
- CG6363 antibody
- Eaf3 antibody
- Esa1p associated factor 3 homolog antibody
see all
画像
-
All lanes : Anti-MRG15 antibody (ab106818) at 0.3 µg/ml
Lane 1 : Mouse liver tissue lysate (in RIPA buffer)
Lane 2 : Rat liver tissue lysate (in RIPA buffer)
Lane 3 : Pig liver tissue lysate (in RIPA buffer)
Lysates/proteins at 35 µg per lane.
Predicted band size: 41 kDa
Additional bands at: 37 kDa. We are unsure as to the identity of these extra bands.Goat Anti-MRG15 / MORF4L1 Antibody (EB06079) - Everest Biotech Ltd
Primary incubation was 1 hour. Detected by chemiluminescence. -
All lanes :
Lane 1 : NIH3T3 cell lysate (in RIPA buffer)
Lane 2 : HepG2 cell lysate (in RIPA buffer)
Lysates/proteins at 35 µg per lane.
Predicted band size: 41 kDa
Additional bands at: 37 kDa. We are unsure as to the identity of these extra bands.Primary incubation was 1 hour. Detected by chemiluminescence.
-
Anti-MRG15 antibody (ab106818) at 0.1 µg/ml + Mouse Liver Lysate in RIPA buffer at 35 µg
Predicted band size: 41 kDa
Primary incubation 1 hour.
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (0)
ab106818 は論文での使用が確認できていません。