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AB19196

Anti-Mouse Serum Albumin 抗体

Anti-Mouse Serum Albumin antibody

3

(1 Review)

|

(20 Publications)

Rabbit Polyclonal Albumin antibody. Suitable for Ie, IHC-FoFr, DID, ICC/IF and reacts with Mouse samples. Cited in 20 publications. Immunogen corresponding to Full Length Protein corresponding to Mouse Alb.

別名を表示する

Alb-1, Alb1, Alb, Albumin

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse

アプリケーション

Ie, ICC/IF, IHC-FoFr, DID

applications

免疫原

Full Length Protein corresponding to Mouse Alb. The exact immunogen used to generate this antibody is proprietary information.

P07724

特異性

By immunoelectrophoresis, the antiserum reacts specifically with mouse Albumin. No reactivity was detected against other mouse serum proteins.

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Reactivity data

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出荷温度及び保存条件

製品の状態
Liquid
精製度
Whole antiserum
バッファー組成
Preservative: 0.1% Sodium azide Constituents: Whole serum
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Mouse serum albumin often referred to as MSA is a significant protein within the mouse circulatory system. It is expressed largely in the liver and released into the bloodstream where it serves multiple physiological roles. Mechanically MSA with a molecular mass of approximately 67 kDa functions as a transporter protein binding and carrying various substances including hormones fatty acids and drugs. This multifunctional nature contributes to maintaining osmotic pressure and ensuring proper distribution of molecules throughout the body.
Biological function summary

This albumin in serum is essential for maintaining blood fluid balance and transporting compounds. It does not form part of a protein complex but it interacts dynamically with other molecules within the serum. Its ability to bind various ligands allows it to play an important role in modulating bioavailability and functionality of these ligands. Additionally MSA regulates the oxidative status of blood by acting as an antioxidant neutralizing free radicals and protecting other proteins from oxidative damage.

Pathways

This mouse albumin shows integration into several critical biological systems. It participates actively in the transport and metabolism pathways where it interacts with proteins such as albumin receptors on cell membranes facilitating transport into cells and tissues. Furthermore it is involved in the homeostasis pathway by regulating fluid distribution and blood volume which are essential for maintaining physiological blood pressure often noted in the context of "130/96 blood pressure" as a reference point in evaluating normal levels.

Mouse serum albumin links to conditions such as liver disease and nephrotic syndrome. These disorders often result from or lead to changes in albumin levels impacting overall health. For instance reduced albumin in serum can lead to edema due to a drop in osmotic pressure often associated with kidney dysfunction. Albumin alongside other key proteins like immunoglobulins becomes a critical marker in diagnosing and understanding the progression of such diseases.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (By similarity). Does not prevent iron uptake by the bacterial siderophore aerobactin (By similarity).
See full target information Alb
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文献 (20)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cellular neuroscience 17:1279385 PubMed38107410

2023

Transient ischemic stroke triggers sustained damage of the choroid plexus blood-CSF barrier.

Applications

Unspecified application

Species

Unspecified reactive species

Yang Chen,Lin Lin,Mohammad Iqbal H Bhuiyan,Kai He,Roshani Jha,Shanshan Song,Victoria M Fiesler,Gulnaz Begum,Yan Yin,Dandan Sun

Particle and fibre toxicology 18:23 PubMed34134756

2021

Repeated oral administration of low doses of silver in mice: tissue distribution and effects on central nervous system.

Applications

Unspecified application

Species

Unspecified reactive species

Camilla Recordati,Marcella De Maglie,Claudia Cella,Simona Argentiere,Saverio Paltrinieri,Silvia Bianchessi,Marco Losa,Fabio Fiordaliso,Alessandro Corbelli,Gianpaolo Milite,Federica Aureli,Marilena D'Amato,Andrea Raggi,Francesco Cubadda,Sabina Soldati,Cristina Lenardi,Eugenio Scanziani

Cell reports 30:4082-4095.e6 PubMed32209470

2020

Chronic Peripheral Inflammation Causes a Region-Specific Myeloid Response in the Central Nervous System.

Applications

Unspecified application

Species

Unspecified reactive species

Patrick Süß,Alana Hoffmann,Tobias Rothe,Zhengyu Ouyang,Wolfgang Baum,Ori Staszewski,Georg Schett,Marco Prinz,Gerhard Krönke,Christopher K Glass,Jürgen Winkler,Johannes C M Schlachetzki

Radiology 291:459-466 PubMed30912718

2019

Rapid Short-pulse Ultrasound Delivers Drugs Uniformly across the Murine Blood-Brain Barrier with Negligible Disruption.

Applications

Unspecified application

Species

Unspecified reactive species

Sophie V Morse,Antonios N Pouliopoulos,Tiffany G Chan,Matthew J Copping,Julien Lin,Nicholas J Long,James J Choi

Skeletal muscle 8:35 PubMed30424786

2018

HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury.

Applications

Unspecified application

Species

Unspecified reactive species

Andrew N Billin,Samuel E Honeycutt,Alan V McDougal,Jaclyn P Kerr,Zhe Chen,Johannes M Freudenberg,Deepak K Rajpal,Guizhen Luo,Henning Fritz Kramer,Robert S Geske,Frank Fang,Bert Yao,Richard V Clark,John Lepore,Alex Cobitz,Ram Miller,Kazunori Nosaka,Aaron C Hinken,Alan J Russell

Molecular therapy. Nucleic acids 10:122-130 PubMed29499927

2018

Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice.

Applications

IHC-P

Species

Unspecified reactive species

Yuan Yan Sin,Laurel L Ballantyne,Christopher R Richmond,Colin D Funk

The Journal of experimental medicine 214:2535-2545 PubMed28694388

2017

Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.

Applications

Unspecified application

Species

Unspecified reactive species

Min Luo,Elle C Flood,Dena Almeida,LunBiao Yan,David A Berlin,Paul M Heerdt,Katherine A Hajjar

Cell death & disease 8:e2883 PubMed28617440

2017

The NF-κB1 is a key regulator of acute but not chronic renal injury.

Applications

RID

Species

Unspecified reactive species

Amy Fearn,Gerhard R Situmorang,Christopher Fox,Fiona Oakley,Rachel Howarth,Caroline L Wilson,Agklinta Kiosia,Michael G Robson,Derek A Mann,Anna Moles,Neil S Sheerin

Diabetes 66:1671-1682 PubMed28270521

2017

Pathogenic Role of in Diabetic Retinopathy Through Downregulation of PPARα.

Applications

Unspecified application

Species

Unspecified reactive species

Qian Chen,Fangfang Qiu,Kelu Zhou,H Greg Matlock,Yusuke Takahashi,Raju V S Rajala,Yanhui Yang,Elizabeth Moran,Jian-Xing Ma

Oncotarget 7:78872-78882 PubMed27713163

2016

Premalignant alteration assessment in liver-like tissue derived from embryonic stem cells by aristolochic acid I exposure.

Applications

Flow Cyt, ICC/IF

Species

Mouse, Mouse

Tong Li,Ke Jin,Dan-Yan Zhu,Lu Li,Zheng-Rong Mao,Bo-Wen Wu,Yi-Fan Wang,Zong-Fu Pan,Lan-Juan Li,Chun-Sheng Xiang,Kun-Kai Su,Yi-Jia Lou
View all publications
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