Anti-Monoacylglycerol Lipase/MGL 抗体 (ab24701)
Key features and details
- Rabbit polyclonal to Monoacylglycerol Lipase/MGL
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Cow, Human, Monkey, African green monkey
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Monoacylglycerol Lipase/MGL antibody
Monoacylglycerol Lipase/MGL 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Monoacylglycerol Lipase/MGL -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Mouse, Rat, Cow, Human, Monkey, African green monkey -
免疫原
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, PBS -
Concentration information loading... -
精製度
IgG fraction -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab24701の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P | (3) |
Use at an assay dependent concentration.
|
| WB | (6) |
1/200. Predicted molecular weight: 33 kDa.
|
| 特記事項 |
|---|
|
IHC-P
Use at an assay dependent concentration. |
|
WB
1/200. Predicted molecular weight: 33 kDa. |
ターゲット情報
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機能
Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. -
組織特異性
Detected in adipose tissue, lung, liver, kidney, brain and heart. -
パスウェイ
Glycerolipid metabolism; triacylglycerol degradation. -
配列類似性
Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family. - Information by UniProt
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参照データベース
- Entrez Gene: 505290 Cow
- Entrez Gene: 11343 Human
- Entrez Gene: 23945 Mouse
- Entrez Gene: 29254 Rat
- Omim: 609699 Human
- SwissProt: Q99685 Human
- SwissProt: O35678 Mouse
- SwissProt: Q8R431 Rat
see all -
別名
- EC 3.1.1.23 antibody
- HU K5 antibody
- HU-K5 antibody
see all
画像
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Western blot - Anti-Monoacylglycerol Lipase/MGL antibody (ab24701)Anti-Monoacylglycerol Lipase/MGL antibody (ab24701) at 1/200 dilution + Rat brown fat at 20 µg
Predicted band size: 33 kDa
Rat brown fat, 20 ug Dilution: 1/200
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (39)
ab24701 は 39 報の論文で使用されています。
- Yadav-Samudrala BJ et al. Effects of acute Δ9-tetrahydrocannabinol on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice. Brain Res 1822:148638 (2024). PubMed: 37858856
- Scipioni L et al. Aβ Chronic Exposure Promotes an Activation State of Microglia through Endocannabinoid Signalling Imbalance. Int J Mol Sci 24:N/A (2023). PubMed: 37047663
- Xu C et al. Inhibitory Neurotransmission Is Sex-Dependently Affected by Tat Expression in Transgenic Mice and Suppressed by the Fatty Acid Amide Hydrolase Enzyme Inhibitor PF3845 via Cannabinoid Type-1 Receptor Mechanisms. Cells 11:N/A (2022). PubMed: 35269478
- Kra G et al. Effects of Environmental Heat Load on Endocannabinoid System Components in Adipose Tissue of High Yielding Dairy Cows. Animals (Basel) 12:N/A (2022). PubMed: 35327191
- Mitra S et al. A role for the endocannabinoid enzymes monoacylglycerol and diacylglycerol lipases in cue-induced cocaine craving following prolonged abstinence. Addict Biol 26:e13007 (2021). PubMed: 33496035