Anti-MHC class I RT Ia 抗体 [OX-18]
Anti-MHC class I RT Ia antibody [OX-18]
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(4 Publications)
Mouse Monoclonal MHC class I RT Ia antibody. Suitable for IP, Flow Cyt, ELISA, IHC-Fr and reacts with Rat samples. Cited in 4 publications.
別名を表示する
RT1 class I gene, RT1 class I gene (A 1), RT1 class Ia locus A, RT1 class Ia, locus A (A1), RT1 class Ia, locus A1, RT1.A1(N), RT1A 1
Reactivity data
製品の詳細
出荷温度及び保存条件
製品の状態
精製方法
精製に関する特記事項
バッファー組成
出荷温度
短期保存期間
短期保存温度
長期保存温度
分注に関する情報
補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
MHC class I RT Ia interacts with peptides within the endoplasmic reticulum and forms a complex with beta-2 microglobulin. This interaction is essential for the stability of the peptide-MHC complex on the cell surface. The formation of these complexes allows for immune recognition and establishment of immune responses. MHC class I RT Ia therefore plays an important role in initiating immune reactions against intracellular pathogens such as viruses.
Pathways
MHC class I RT Ia participates in the antigen processing and presentation pathway a fundamental aspect of adaptive immunity. It interacts with the transporter associated with antigen processing (TAP) proteins which transport peptides to the endoplasmic reticulum. Apart from that it also engages in the pathway involving cytotoxic T lymphocyte activation where it directly influences T-cell receptor signaling.
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文献 (4)
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Experimental neurology 282:78-85 PubMed27235932
2016
Applications
IHC
Species
Rat
Immunology letters 135:118-23 PubMed20974178
2010
Applications
Unspecified application
Species
Unspecified reactive species
Transplantation proceedings 25:2806-7 PubMed8212242
1993
Applications
Unspecified application
Species
Unspecified reactive species
European journal of immunology 12:237-43 PubMed6178598
1982
Applications
Unspecified application
Species
Unspecified reactive species
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