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Anti-Mesothelioma 抗体 [HBME-1] (ab2383)

Submit a review Q&A (1)References (4)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)

Key features and details

  • Mouse monoclonal [HBME-1] to Mesothelioma
  • Suitable for: IHC-P
  • Reacts with: Human
  • Isotype: IgM

製品の概要

  • 製品名

    Anti-Mesothelioma antibody [HBME-1]

  • 製品の詳細

    Mouse monoclonal [HBME-1] to Mesothelioma

  • 由来種

    Mouse

  • 特異性

    This antibody reacts with an unknown antigen on microvilli of mesothelioma cells. It stains normal mesothelial cells as well as epithelial mesothelimias in a thick membrane pattern due to abundant lung microvilli on the surface of these cells.

  • アプリケーション

    適用あり: IHC-Pmore details

  • 種交差性

    交差種: Human

  • 免疫原

    Tissue, cells or virus corresponding to Mesothelioma. Suspension of human mesothelioma cells from patients with malignant epithelial mesothelioma

  • ポジティブ･コントロール

    • Mesothelioma.

  • 特記事項

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

  • 製品の状態

    Liquid

  • 保存方法

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • バッファー

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituent: 1% BSA
  • Concentration information loading...

  • 精製度

    Purified IgM

  • ポリ/モノ

    モノクローナル

  • クローン名

    HBME-1

  • ミエローマ

    unknown

  • アイソタイプ

    IgM

  • 軽鎖の種類

    unknown

  • 研究分野

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab2383の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
IHC-P
1/15 - 1/25. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Primary incubation for 30 minutes at room temperature.
特記事項
IHC-P
1/15 - 1/25. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Primary incubation for 30 minutes at room temperature.

ターゲット情報

  • 関連性

    Mesothelioma is a rare form of carcinoma of the mesothelial cells which that normally line the body cavities, including the pleura, peritoneum, pericardium, and testis. It may be localized or diffuse. Most, but not all, cases of pleural malignant mesothelioma are associated with asbestos exposure.

  • 別名

    • Malignant mesothelioma susceptibility to antibody
    • MMS antibody

画像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
    Formalin-fixed, paraffin-embeded human mesothelioma tissue stained for Mesothelioma using ab2383 at 1/15 dilution in immunohistochemical analysis. Antigen retrieval with citrate buffer pH 6.0
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
    ab2383 staining human mesothelioma by IHC-P.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelioma antibody [HBME-1] (ab2383)
    Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human mesothelioma tissue, staining Mesothelioma with ab2383.

参考文献 (4)

ab2383 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab2383 は 4 報の論文で使用されています。

  • Chang Z  et al. PIWI-interacting RNAs piR-13643 and piR-21238 are promising diagnostic biomarkers of papillary thyroid carcinoma. Aging (Albany NY) 12:9292-9310 (2020). PubMed: 32428871
  • Chernova T  et al. Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf). Curr Biol 27:3302-3314.e6 (2017). PubMed: 29112861
  • Manzoni M  et al. Solid cell nests of the thyroid gland: morphological, immunohistochemical and genetic features. Histopathology 68:866-74 (2016). PubMed: 26334919
  • Pagni F  et al. Proteomics in thyroid cytopathology: Relevance of MALDI-imaging in distinguishing malignant from benign lesions. Proteomics 16:1775-84 (2016). PubMed: 27029406

レビューと Q&A

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Question

What is the concentration of this antibody?

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Answer

Thank you for contacting Abcam regarding ab2383.


The average concentration of this antibody is 45mg/L. If you have a specific lot number, I can check for that concentration as well.


I hope this information is helpful. Please do not hesitate to contact us if you have any additional questions.

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