Anti-MD1 抗体 (ab45424)
Key features and details
- Rabbit polyclonal to MD1
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-MD1 antibody
MD1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to MD1 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic 15 amino acid peptide from near the center of human MD1
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ポジティブ･コントロール
- Daudi cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
This antibody is an immunoaffinity purified IgG -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab45424の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use a concentration of 2.5 µg/ml.
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| WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 18 kDa).
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| 特記事項 |
|---|
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IHC-P
Use a concentration of 2.5 µg/ml. |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 18 kDa). |
ターゲット情報
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機能
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression. -
組織特異性
Highly expressed in B-cells, monocytes and tonsil. -
細胞内局在
Secreted > extracellular space. Associated with CD180 at the cell surface. - Information by UniProt
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参照データベース
- Entrez Gene: 9450 Human
- Omim: 605241 Human
- SwissProt: O95711 Human
- Unigene: 653138 Human
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別名
- BPAD antibody
- dJ80N2.1 antibody
- Ly 86 antibody
see all
画像
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Western blot - Anti-MD1 antibody (ab45424)Anti-MD1 antibody (ab45424) at 2 µg/ml + Daudi cell lysate at 15 µg
Predicted band size: 18 kDa
Observed band size: 27 kDa why is the actual band size different from the predicted? -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MD1 antibody (ab45424)ab45424 at 2.5µg/ml staining MD1 in human spleen tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded tissue sections).
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab45424 は 2 報の論文で使用されています。
- Song Z et al. Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer's Disease in 5XFAD Mouse Model. Front Genet 11:565479 (2020). PubMed: 33250918
- Yang HJ et al. Knockout of MD1 contributes to sympathetic hyperactivity and exacerbates ventricular arrhythmias following heart failure with preserved ejection fraction via NLRP3 inflammasome activation. Exp Physiol 105:966-978 (2020). PubMed: 32240565