Anti-MC4-R 抗体 [EPR6534(2)(ABC)] (ab150419)
![Western blot - Anti-MC4-R antibody [EPR6534(2)(ABC)] (ab150419)](https://www.abcam.co.jp/ps/products/150/ab150419/Images/ab150419-157069-anti-mc4-r-antibody-epr65342abc-western-blot.jpg "Western blot - Anti-MC4-R antibody [EPR6534(2)(ABC)] (ab150419)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6534(2)(ABC)] to MC4-R
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
製品の概要
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製品名
Anti-MC4-R antibody [EPR6534(2)(ABC)]
MC4-R 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR6534(2)(ABC)] to MC4-R -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- 293T; MCF7; JAR; SH-SY5Y; C6; RAW 264.7; PC12 and NIH 3T3 cell lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20ºC. -
バッファー
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
EPR6534(2)(ABC) -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab150419の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000 - 1/10000. Predicted molecular weight: 36 kDa.
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| 特記事項 |
|---|
|
WB
1/1000 - 1/10000. Predicted molecular weight: 36 kDa. |
追加情報
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
ターゲット情報
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機能
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase. -
組織特異性
Brain, placental, and gut tissues. -
関連疾患
Defects in MC4R are a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 4160 Human
- Entrez Gene: 17202 Mouse
- Entrez Gene: 25635 Rat
- Omim: 155541 Human
- SwissProt: P32245 Human
- SwissProt: P56450 Mouse
- SwissProt: P70596 Rat
- Unigene: 532833 Human
see all -
別名
- MC4 Receptor antibody
- MC4-R antibody
- MC4R antibody
see all
画像
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Western blot - Anti-MC4-R antibody [EPR6534(2)(ABC)] (ab150419)All lanes : Anti-MC4-R antibody [EPR6534(2)(ABC)] (ab150419) at 1/1000 dilution
Lane 1 : 293T cell lysate
Lane 2 : MCF7 cell lysate
Lane 3 : JAR cell lysate
Lane 4 : SH-SY5Y cell lysate
Lane 5 : C6 cell lysate
Lane 6 : RAW 264.7 cell lysate
Lane 7 : PC12 cell lysate
Lane 8 : NIH 3T3 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 36 kDa -
![Anti-MC4-R antibody [EPR6534(2)(ABC)] (ab150419)](https://www.abcam.co.jp/ps/products/150/ab150419/Images/ab150419-2-benefits-of-recombinant-antibodies.png)
Anti-MC4-R antibody [EPR6534(2)(ABC)] (ab150419)
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab150419 は論文での使用が確認できていません。