Anti-Malondialdehyde 抗体 (ab27642)
Key features and details
- Rabbit polyclonal to Malondialdehyde
- Suitable for: ELISA, Conjugation, WB
- Isotype: IgG
製品の概要
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製品名
Anti-Malondialdehyde antibody
Malondialdehyde 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Malondialdehyde -
由来種
Rabbit -
特異性
This antibody specifically binds to Malondialdehyde LDL and other Malondialdehyde modified proteins. -
アプリケーション
適用あり: ELISA, Conjugation, WBmore details -
免疫原
Chemical/ Small Molecule MDA modified protein
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 0.0292% EDTA, 0.435% Sodium chloride, 30% Glycerol -
Concentration information loading...
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特記事項(精製)
This antibody was purified by MDA modified protein Sepharose affinity column. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab27642の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent concentration.
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Conjugation |
Use at an assay dependent concentration.
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WB | (3) |
Use at an assay dependent concentration.
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特記事項 |
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ELISA
Use at an assay dependent concentration. |
Conjugation
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
ターゲット情報
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関連性
Malondialdehyde (MDA) is a natural product formed in all mammalian cells as a product of lipid peroxidation. MDA is a highly reactive three carbon dialdehyde produced as a byproduct of polyunsaturated fatty acid peroxidation and arachidonic acid metabolism. MDA readily combines with several functional groups on molecules including proteins, lipoproteins, and DNA. It reacts with DNA to form adducts to deoxyguanosine and deoxyadenosine. The major adduct to DNA is a pyrimidopurinone called M1G which appears to be a major endogenous DNA adduct in human beings that may contribute significantly to cancer linked to lifestyle and dietary factors. MDA modified proteins may show altered physico chemical behavior and antigenicity. MDA is toxic and has been implicated in aging mutagenesis, carcinogenesis, diabetic nephropathy and radiation damage. Increased expression of MDA has been reported in the brains of Alzheimer's patients. Antibodies to MDA will help to visualize the MDA adducts. -
別名
- 1133 Tetramethoxypropane antibody
- MDA antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (34)
ab27642 は 34 報の論文で使用されています。
- Prasad A et al. Imaging and Characterization of Oxidative Protein Modifications in Skin. Int J Mol Sci 24:N/A (2023). PubMed: 36835390
- Zahid S et al. The Geroprotective Drug Candidate CMS121 Alleviates Diabetes, Liver Inflammation, and Renal Damage in db/db Leptin Receptor Deficient Mice. Int J Mol Sci 24:N/A (2023). PubMed: 37047807
- Lian Z et al. Epicatechin Inhibited Lipid Oxidation and Protein Lipoxidation in a Fish Oil-Fortified Dairy Mimicking System. Foods 12:N/A (2023). PubMed: 37048380
- Steffen JBM et al. Combined effects of salinity and intermittent hypoxia on mitochondrial capacity and reactive oxygen species efflux in the Pacific oyster, Crassostrea gigas. J Exp Biol 226:N/A (2023). PubMed: 37470191
- Mohammed AI et al. Assessment of Oxidative Stress-Induced Oral Epithelial Toxicity. Biomolecules 13:N/A (2023). PubMed: 37627304